|Smith, Timothy - Tim|
Submitted to: Journal of Animal Science Supplement
Publication Type: Abstract Only
Publication Acceptance Date: 4/14/2008
Publication Date: 7/7/2008
Citation: Garcia, M.D., Matukumalli, L., Wheeler, T.L., Shackelford, S.D., Koohmaraie, M., Smith, T.P., Casas, E. 2008. Markers on bovine chromosome 20 associated with fat related traits and incidence of contracting bovine respiratory disease [abstract]. Journal of Animal Science Supplement. 86(E-Suppl. 2):210. Abstract #W54.
Technical Abstract: The objective of this study was to assess the association of single nucleotide polymorphism (SNP) markers with incidence of bovine respiratory disease (BRD) and fat related traits. Steers from the Cycle 7 of the Germplasm Evaluation Program (GPE7; n=565) were used. The GPE7 population comprises animals derived from 7 breeds: Angus, Charolais, Gelbvieh, Hereford, Limousin, Red Angus, and Simmental. Markers were located between centimorgan 14.5 and 20.3 on bovine chromosome 20 (BTA20). One SNP was associated with incidence of BRD and yield grade (P < 0.008). Animals inheriting the CT genotype had the lowest yield grade (2.82 ± 0.09), and the highest incidence of BRD (0.33 ± 0.04) when compared to those inheriting the CC genotype (3.12 ± 0.19, and 0.17 ± 0.02 for yield grade and incidence of BRD, respectively). Animals inheriting the TT genotype were observed in low frequency (n=11) and were excluded from the analysis. A second SNP was associated (P < 0.007) with incidence of BRD, dressing percentage and estimated kidney, pelvic and heart fat percentage (KPH). Steers inheriting the AG genotype had the lowest incidence of BRD and KPH (0.15 ± 0.03 and 2.22 ± 0.05, respectively) when compared to animals inheriting the AA genotype (0.28 ± 0.03 and 2.39 ± 0.05, respectively). Animals inheriting the GG genotype had an intermediate incidence of BRD (0.21 ± 0.03), when compared to animals inheriting the AA and AG genotypes, and similar KPH as those inheriting the AA genotype (2.35 ± 0.05). Animals inheriting the AG and GG genotypes had lower dressing percentages (62.2 ± 0.13 and 62.2 ± 0.12, respectively) when compared to animals inheriting the AA genotype (62.8 ± 0.13). Further evaluation of SNP markers in this region of BTA20 is needed to identify optimal marker combinations associated with BRD and fat related traits.