Submitted to: Phytopathology
Publication Type: Abstract Only
Publication Acceptance Date: 7/31/2005
Publication Date: 5/20/2005
Citation: Abril, M., Curry, K.J., Wedge, D.E., Smith, B.J. 2005. Sensitivity of selected plant pathogenic fungi to sampangine and its analogs. Phytopathology vol.95, no.6:S2. Interpretive Summary:
Technical Abstract: Sampangine is a novel natural-based fungicide which we tested in vitro for efficacy for control of several economically important plant pathogens. Sensitivities of Botrytis cinerea, Colletotrichum acutatum, C. fragariae, C. gloeosporioides, and Fusarium oxysporum to sampangine and seven of its analogs were determined based on hyphal growth inhibition. In vitro microtiter assays demonstrated that sampangine was more efficacious than its analogs and than most of the commercial fungicides tested. A sampangine analog, 4-bromosampangine, caused morphological abnormalities in the germ tubes of B. cinerea and C. fragariae suggesting a physical mode of action, indicating that appressorial formation and hyphal growth, but not conidial germination, are impaired. This suggests the possibility that 4-bromosampangine, unlike most fungicides, may protect hosts after fungi have germinated.