Submitted to: American Chemical Society Symposium Series
Publication Type: Book / chapter
Publication Acceptance Date: 7/1/2006
Publication Date: 8/1/2006
Citation: Breksa III, A.P., Manners, G.D., Jacobs, R.A., Hasegawa, S. 2006. Citrus Limonoid Bioavailability in Humans. In: ACS Symposium Series No. 936, Potential Health Benefits of Citrus; Patil, B.S.; Turner, N.D.; Miller, E.G.; Brodbelt, J.S. Washington, DC: American Chemical Society. p. 95-101. Interpretive Summary: Citrus is recognized as one of the most healthful components of the human diet. Much of the contribution of citrus to human health and nutrition can be attributed to secondary metabolites present in citrus including anti-oxidants (ascorbic acid, flavanones, simple phenolics, carotenoids), folate and pectin. Limonoids, complex triterpenoid compounds, constitute another important class of secondary metabolites that occur in citrus in significant quantities. In this chapter, the results from limonoid human bioavailability study are compared to the bioavailability results of other citrus secondary metabolites, and future research directions presented.
Technical Abstract: The absorption, metabolism and bioavailability of citrus limonoids in human subjects administered high doses of pure limonin glucoside has been reported. In this chapter, the results from this study are compared to the bioavailability results of other citrus secondary metabolites, and future research directions presented.