Submitted to: Feedinfo News Service
Publication Type: Review Article
Publication Acceptance Date: 8/6/2004
Publication Date: 8/11/2004
Citation: Carlson, S.A. 2004. Salmonella strain DT104: multiple new abilities to cause disease and the relationship to multiple antibiotic resistances. Feedinfo News Service. Available: http://www/feedinfo.com/console/PageViewer.aspx?page=144622.
Technical Abstract: Salmonella is a foodborne bacterium that causes intestinal disease in numerous hosts throughout the world. One particular strain, designated as DT104, has set itself apart because of two factors: the ability to cause disease that is either atypical for Salmonella or more severe than what is normally observed in Salmonella infections; and the ability to resist numerous antibiotics. The enhanced ability to cause disease has been especially noted in humans and cattle. Treatment failures, due to the use of ineffective antibiotics that kill only bacteria that compete with Salmonella for nutrients, may underlie some of the severity of infections. However, it now appears that the augmentation of virulence is related to genetic elements associated with a cluster of antibiotic resistance genes.