Submitted to: Book Chapter
Publication Type: Book / Chapter
Publication Acceptance Date: 9/10/2005
Publication Date: N/A
Technical Abstract: Cholecystokinin (CCK) is a hormone found within the brain and gastrointestinal system that has diverse roles in sexual behavior, learning, and pain. Most importantly and the focus of this definition is CCK's effect on gastrointestinal (GI) function and feelings of satiety. Cholecystokinin originates as a preprohormone consisting of 115 amino acids, though after further processing can be found in many forms including: CCK-58, CCK-33, and CCK-8. Relative potency of each form varies with location and species. Typically, plasma CCK concentrations will rise within 15 minutes of a meal's initiation, peak after 30 minutes, then fall to basal concentrations over 3-5 hours.