Submitted to: Book Chapter
Publication Type: Book / Chapter
Publication Acceptance Date: 1/1/2003
Publication Date: 8/1/2003
Citation: FLETCHER, J.C. STEM CELL MAINTENANCE IN HIGHER PLANTS. Lanza, R.P., editor. Academic Press, New York, NY. Handbook of Adult and Fetal Stem Cells. 2003. [IN PRESS]
Interpretive Summary: This book chapter is an exhaustive summary of the current state of knowledge concerning the molecular mechanisms that maintain stem cells in higher plant systems. Particular emphasis is placed on gene activities, expression patterns, and intercellular signal transduction in stem cell populations.
Technical Abstract: Until recently, little has been known about the molecular mechanisms that establish and maintain stem cell populations in the apical meristems of plants. However, genetic and molecular evidence now convincingly demonstrates that maintenance of the meristematic state throughout development is mediated by a complex network of positive and negative regulatory interactions. Much of the data has come from studies using the model plant Arabidopsis thaliana, a member of the mustard family and a relative of broccoli and cauliflower, on which this article will focus.