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ARS Home » Pacific West Area » Davis, California » Western Human Nutrition Research Center » Obesity and Metabolism Research » Research » Research Project #440956

Research Project: Metagenomic Approaches to Dietary Interventions

Location: Obesity and Metabolism Research

Project Number: 2032-51530-025-072-S
Project Type: Non-Assistance Cooperative Agreement

Start Date: Sep 1, 2021
End Date: Sep 1, 2023

Objective:
The objective of this Non-Assistance Cooperative Agreement (NACA) is to facilitate the joint research of metagenomics and metabolomics research at the Western Human Nutrition Research Center (WHNRC), located on the campus of the University of California Davis (UC Davis). The proposed research focus is metabolic individuality in response to the Dietary Guidelines for Americans and the relationship between an individual’s response and disease prevention. Studies will include: Improving Public Health by Understanding Diversity in Diet, Body, and Brain Interactions; and Novel Functions and Biomarkers for Vitamins and Minerals.

Approach:
UC Davis will support clinical studies conducted in the WHNRC by employing full and part time technical and medical personnel required to accomplish the proposed research. These include, but are not limited to, an Assistant Project Scientist(s), and/or an equivalent candidate(s) to provide project management and advanced statistical data analysis of human metagenomic and metabolomic analysis. These collaborating technical and scientific staff will provide a variety of support including: dietary analysis, project management, analytical chemistry, and statistical data analysis. Specific analysis will include 16S microbial diversity analysis using appropriate bioinformatics packages including but not limited to Quantitative Insights Into Microbial Ecology (QIIME2), development and execution of custom python scripts and statistical analysis and visualization using Rstudio.