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ARS Home » Pacific West Area » Davis, California » Western Human Nutrition Research Center » Obesity and Metabolism Research » People & Locations » Catherine Kirschke
Catherine P Kirschke
Obesity and Metabolism Research
Biologist

Phone: (530) 754-5757
Fax: (530) 752-5271

430 W HEALTH SCIENCES DRIVE
DAVIS, CA 95616

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Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Effects of a genetic variant rs13266634 in the zinc transporter 8 gene (SLC30A8) on insulin and lipid levels before and after a high-fat mixed macronutrient tolerance test in U.S. adults Reprint Icon - (Peer Reviewed Journal)
Yang, Z., Wang, Y.E., Kirschke-Schneide, C.P., Stephensen, C.B., Newman, J.W., Keim, N.L., Cai, Y., Huang, L. 2023. Effects of a genetic variant rs13266634 in the zinc transporter 8 gene (SLC30A8) on insulin and lipid levels before and after a high-fat mixed macronutrient tolerance test in U.S. adults. Journal of Trace Elements in Medicine and Biology. 77. https://doi.org/10.1016/j.jtemb.2023.127142.
Identification of novel compound heterozygous mutations in the SLC30A7 (ZNT7) gene in two French brothers with stunted growth, testicular hypoplasia, and bone marrow failure Reprint Icon - (Peer Reviewed Journal)
Huang, L., Yang, Z., Kirschke-Schneide, C.P., Prouteau, C., Copin, M., Bonneau, D., Pellier, I., Coutant, R., Miot, C., Ziegler, A. 2023. Identification of novel compound heterozygous mutations in the SLC30A7 (ZNT7) gene in two French brothers with stunted growth, testicular hypoplasia, and bone marrow failure. Human Molecular Genetics. 00(00):1-16. https://doi.org/10.1093/hmg/ddad033.
Trimethylamine N-Oxide response to a mixed macronutrient tolerance test in a cohort of United States adults unmedicated for cardiometabolic disease Reprint Icon - (Peer Reviewed Journal)
James, K.L., Gertz, E.R., Kirschke-Schneide, C.P., Allaye, H., Huang, L., Kable, M.E., Newman, J.W., Stephensen, C.B., Bennett, B.J. 2023. Trimethylamine N-Oxide response to a mixed macronutrient tolerance test in a cohort of United States adults unmedicated for cardiometabolic disease. International Journal of Molecular Sciences. 24(3). https://doi.org/10.3390/ijms24032074.
SNPs in apolipoproteins contribute to sex-dependent differences in blood lipids before and after a high-fat dietary challenge in healthy U.S. adults Reprint Icon - (Peer Reviewed Journal)
Wang, Y.E., Kirschke-Schneide, C.P., Woodhouse, L.R., Bonnel, E.L., Stephensen, C.B., Bennett, B.J., Newman, J.W., Keim, N.L., Huang, L. 2022. SNPs in apolipoproteins contribute to sex-dependent differences in blood lipids before and after a high-fat dietary challenge in healthy U.S. adults. Biomed Central (BMC) Nutrition. 8. Article 95. https://doi.org/10.1186/s40795-022-00592-x.
The Znt7-null mutation has sex dependent effects on the gut microbiota and goblet cell population in the mouse colon Reprint Icon - (Peer Reviewed Journal)
Kable, M.E., Riazati, N., Kirschke, C.P., Zhao, J., Tepaamorndech, S., Huang, L. 2020. The Znt7-null mutation has sex dependent effects on the gut microbiota and goblet cell population in the mouse colon. PLoS ONE. 15(9). Article e0239681. https://doi.org/10.1371/journal.pone.0239681.
Association of lactase persistence genotypes (rs4988235) and ethnicity with dairy intake in a healthy U.S. population Reprint Icon - (Peer Reviewed Journal)
Chin, E.L., Huang, L., Bouzid, Y.Y., Kirschke, C.P., Durbin-Johnson, B., Baldiviez, L.M., Bonnel, E.L., Keim, N.L., Korf, I., Stephensen, C.B., Lemay, D.G. 2019. Association of lactase persistence genotypes (rs4988235) and ethnicity with dairy intake in a healthy U.S. population. Nutrients. 11(8):1860. https://doi.org/10.3390/nu11081860.
Temporal changes in postprandial blood transcriptomes reveal subject-specific pattern of expression of innate immunity genes after a high-fat meal Reprint Icon - (Peer Reviewed Journal)
Lemay, D.G., Huang, S., Huang, L., Alkan, Z., Kirschke, C.P., Burnett, D.J., Wang, Y., Hwang, D.H. 2019. Temporal changes in postprandial blood transcriptomes reveal subject-specific pattern of expression of innate immunity genes after a high-fat meal. Journal of Nutritional Biochemistry. 72:108209. https://doi.org/10.1016/j.jnutbio.2019.06.007.
Subcongenic analysis of a quantitative trait locus affecting body weight and glucose metabolism in zinc transporter 7 (znt7)-knockout mice Reprint Icon - (Peer Reviewed Journal)
Huang, L., Tepaamorndech, S., Kirschke, C.P., Cai, Y., Zhao, J., Cao, X., Rao, A. 2019. Subcongenic analysis of a quantitative trait locus affecting body weight and glucose metabolism in zinc transporter 7 (znt7)-knockout mice. BioMed Central (BMC) Genetics. 20:19. https://doi.org/10.1186/s12863-019-0715-2.
SLC30A family expression in the pancreatic islets of humans and mice: cellular localization in the ß-cells Reprint Icon - (Peer Reviewed Journal)
Cai, Y., Kirschke, C.P., Huang, L. 2018. SLC30A family expression in the pancreatic islets of humans and mice: cellular localization in the ß-cells. Journal of Molecular Histology. 49(2):133-145. https://doi.org/10.1007/s10735-017-9753-0.
Aberrant fatty acid metabolism in the skeletal muscle contributes to insulin resistance in zinc transporter 7 (Znt7) knockout mice Reprint Icon - (Peer Reviewed Journal)
Huang, L., Tepaamorndech, S., Kirschke, C.P., Newman, J.W., Keyes, W.R., Pedersen, T.L. 2018. Aberrant fatty acid metabolism in the skeletal muscle contributes to insulin resistance in zinc transporter 7 (Znt7) knockout mice. Journal of Biological Chemistry. 293(20):7549-7563. doi:10.1074/jbc.M117.817692.
ZNT7 binds to CD40 and influences CD154-triggered p38 MAPK activity in B lymphocytes-a possible regulatory mechanism for zinc in immune function - (Peer Reviewed Journal)
Tepaamorndech, S., Oort, P.J., Kirschke, C.P., Yimeng, C., Huang, L. 2017. ZNT7 binds to CD40 and influences CD154-triggered p38 MAPK activity in B lymphocytes-a possible regulatory mechanism for zinc in immune function. FEBS Open Bio. 7(5):675–690. doi: 10.1002/2211-5463.12211.
Down-regulation of zinc transporter 8 (SLC30A8) in pancreatic beta-cells promotes cell survival - (Peer Reviewed Journal)
Huang, L., Kirschke, C.P. 2016. Down-regulation of zinc transporter 8 (SLC30A8) in pancreatic beta-cells promotes cell survival. Austin Journal of Endocrinology and Diabetes. 3:1037.
Down-regulation of zinc transporter 8 (SLC30A8) in pancreatic beta-cells promotes cell survival. - (Peer Reviewed Journal)
Huang, L., Kirschke, C.P. 2016. Down-regulation of zinc transporter 8 (SLC30A8) in pancreatic beta-cells promotes cell survival.. Austin Journal of Endocrinology and Diabetes. 3(1):1-8.
Zinc transporter 7 deficiency affects lipid synthesis in adipocytes by inhibiting insulin-dependent Akt activity and glucose uptake - (Peer Reviewed Journal)
Tepaamorndech, S., Kirschke, C.P., Pedersen, T.L., Keyes, W.R., Newman, J.W., Huang, L. 2015. Zinc transporter 7 deficiency affects lipid synthesis in adipocytes by inhibiting insulin-dependent Akt activity and glucose uptake. FEBS Journal. 283(2):378-394. doi: 10.1111/febs.13582.
Linking cellular zinc status to body weight and fat mass: mapping quantitative trait loci in Znt7 knockout mice - (Peer Reviewed Journal)
Dietary strawberry powder reduces blood glucose concentrations in obese and lean C57BL/6 mice and selectively lowers plasma C-reactive protein in lean mice - (Peer Reviewed Journal)
Parelman, M.A., Storms, D.H., Kirschke, C.P., Huang, L., Zunino, S.J. 2012. Dietary strawberry powder reduces blood glucose concentrations in obese and lean C57BL/6 mice and selectively lowers plasma C-reactive protein in lean mice. British Journal of Nutrition. 1-11. DOI: 10.1017/S0007114512000037.
A null-mutation in the Znt7 gene accelerates prostate tumor formation in a transgenic adenocarcinoma mouse prostate model - (Peer Reviewed Journal)
Tepaamorndech, S., Huang, L., Kirschke, C.P. 2011. A null-mutation in the Znt7 gene accelerates prostate tumor formation in a transgenic adenocarcinoma mouse prostate model. Cancer Letters. 308 (2011) 33-42.
Over-expression of ZnT7 increases insulin synthesis and secretion in pancreatic beta-cells by promoting insulin gene transcription - (Peer Reviewed Journal)
Huang, L., Mi, Y., Kirschke, C.P. 2010. Over-expression of ZnT7 increases insulin synthesis and secretion in pancreatic beta-cells by promoting insulin gene transcription. Experimental Cell Research. 2010 Volume 316, Issue 16 2630-2643
Expression of ZNT (SLC30) family members in the epithelium of the mouse prostate during sexual maturation - (Peer Reviewed Journal)
Kirschke, C.P., Huang, L. 2008. Expression of ZNT (SLC30) family members in the epithelium of the mouse prostate during sexual maturation. Journal of Histochemistry and Cytochemistry (2008) 39:359-370.
Znt7 (Slc30a7)-DEFICIENT MICE DISPLAY REDUCED BODY ZINC STATUS AND BODY FAT ACCUMULATION - (Peer Reviewed Journal)
Huang, L., Yu, Y., Kirschke, C.P., Gertz, E.R., Kent K.C., L. 2008. Znt7 (Slc30a7)-Deficient Mice Display Rreduced Body ZincC Status and Body Fat Accumulation. Journal of Biological Chemistry. 282,51:37053-37063, 2007.
A DI-LEUCINE SORTING SIGNAL IN ZIP1 (SLC39A1) MEDIATES ENDOCYTOSIS OF THE PROTEIN - (Peer Reviewed Journal)
Huang, L., Kirschke, C.P. A di-leucine sorting signal in zip1 (slc39a1) mediates endocytosis of the protein. FEDERATION OF EUROPEAN BIOCHEMICAL SOCIETY, 274: 3986-3997, 2007.
IMMUNOHISTOCHEMICAL ANALYSIS OF ZNT1, 4, 5, 6, AND 7 IN THE MOUSE GASTROINTESTINAL TRACT - (Peer Reviewed Journal)
Yu, Y.Y., Kirschke, C.P., Huang, L. 2006. IMMUNOHISTOCHEMICAL ANALYSIS OF ZNT1, 4, 5, 6, AND 7 IN THE MOUSE GASTROINTESTINAL TRACT. Journal of Histochemistry and Cytochemistry. Vol. 55(3):223-234, 2006.
DECREASED INTRACELLULAR ZINC IN HUMAN TUMORIGENIC PROSTATE EPITHELIAL CELLS: A POSSIBLE ROLE IN PROSTATE CANCER PROGRESSION - (Peer Reviewed Journal)
Huang, L., Kirschke, C.P., Zhang, Y. Decreased intracellular zinc in human tumorigenic prostate epithelial cells: a possible role in prostate cancer progression. Cancer Cell International 2006, 6:10, 2006.
ZIP7 GENE (SLC39A7) ENCODES A ZINC TRANSPORTER INVOLVED IN ZINC HOMEOSTASIS OF THE GOLGI APPARATUS - (Peer Reviewed Journal)
Huang, L., Kirschke, C.P., Zhang, Y., Yu, Y. 2005. ZIP7 GENE (SLC39A7) ENCODES A ZINC TRANSPORTER INVOLVED IN ZINC HOMEOSTASIS OF THE GOLGI APPARATUS. Journal of Biological Chemistry 280(15):15456-15463, 2005.
INVESTIGATION OF LYMPHOCYTE GENE EXPRESSION FOR USE AS BIOMARKERS FOR ZINC STATUS IN HUMANS - (Peer Reviewed Journal)
Andree, K.B., Kim, J., Kirschke, C.P., Gregg, J.P., Paik, H., Joung, H., Woodhouse, L.R., King, J., Huang, L. 2004. Investigation of lymphocyte gene expression for use as biomarkers for zinc status in humans. Journal of Nutrition. Journal of Nutrition. 134:1716-1723, 2004.
ZNT7, A NOVEL MAMMALIAN ZINC TRANSPORTER, ACCUMULATES ZINC IN THE GOLGI APPARATUS - (Peer Reviewed Journal)
Kirschke, C.P., Huang, L. 2004. Znt7, a novel mammalian zinc transporter, accumulates zinc in the golgi apparatus. Journal of Biological Chemistry. 278:4096-103, 2004.