Paula Chen
Plant Genetics Research
Research Molecular Biologist
Phone: (573) 882-5209
Fax:
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Publications
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Fetal bone engraftment reconstitutes the immune system in pigs with severe combined immunodeficiency
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Monarch, K., Yoon, J., Uh, K., Reese, E., Canaveral Restrepo, D., De Carvalho Madrid, D., Touchard, L., Spate, L.D., Samuel, M.S., Driver, J.P., Lim, J., Schlink, S., Whitworth, K.M., Wells, K.D., Prather, R.S., Chen, P.R., Lee, K. 2024. Fetal bone engraftment reconstitutes the immune system in pigs with severe combined immunodeficiency. Lab Animal. 53:276-286. https://doi.org/10.1038/s41684-024-01439-7.
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Accelerating genomic improvement in pigs by using reproductive biotechnologies
- (Book / Chapter)
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Impaired skeletal development by disruption of presenilin-1 in pigs and generation of novel pig models for Alzheimer’s disease
- (Peer Reviewed Journal)
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Uh, K., Monarch, K., Reese, E.D., Rodriguez, K., Yoon, J.D., Spate, L.D., Samuel, M.S., Koh, S., Chen, P.R., Jarome, T., Allen, T., Prather, R.S., Lee, K. 2024. Impaired skeletal development by disruption of presenilin-1 in pigs and generation of novel pig models for Alzheimer’s disease. Journal of Alzheimer's Disease. 101(2):445-461. https://doi.org/10.3233/JAD-231297.
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Novel off-targeting events identified after genome wide analysis of CRISPR-Cas edited pigs
- (Peer Reviewed Journal)
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Redel, B.K., Yoon, J., Reese, E., An, H., Uh, K., Chen, P.R., Prather, R.S., Lee, K. 2024. Novel off-targeting events identified after genome wide analysis of CRISPR-Cas edited pigs. The CRISPR Journal. 7(3): 141 - 149. https://doi.org/10.1089/crispr.2024.0012.
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Porcine-specific expression of the three functional CYP19 paralogs in early conceptus, placenta, and gonads
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Lucas, C.G., Sullivan, R.M., Pfeiffer, C.A., Chen, P.R., Kim, J., Sponchiado, M.S., Conley, A.J., Prather, R.S., Wells, K.D., Geisert, R.D. 2023. Porcine-specific expression of the three functional CYP19 paralogs in early conceptus, placenta, and gonads. Reproduction. 166(4):263-269. https://doi.org/10.1530/REP-23-0189.
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Inactivation of growth differentiation factor 9 blocks folliculogenesis in pigs
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Chen, P.R., Uh, K., Monarch, K., Spate, L., Reese, E., Prather, R., Lee, K. 2023. Inactivation of growth differentiation factor 9 blocks folliculogenesis in pigs. Biology of Reproduction. 108(4):611-618. https://doi.org/10.1093/biolre/ioad005.
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