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United States Department of Agriculture

Agricultural Research Service

Related Topics

James Zhu
Foreign Animal Disease Research
General Biological Science

Phone: (631) 323-3186
Fax: (631) 323-3006

40550 ROUTE 25
ORIENT POINT , NY 11957

Projects
COUNTERMEASURES TO CONTROL FOREIGN ANIMAL DISEASES OF SWINE
Appropriated (D)
  Accession Number: 422018
Intervention Strategies to Support the Global Control and Eradication of Foot-and-Mouth Disease Virus(FMDV)
Appropriated (D)
  Accession Number: 422203
ECOLOGY AND PATHOGENESIS OF RE-EMERGING VESICULAR STOMATITIS VIRUS (VSV) IN NORTH AMERICA
Appropriated (D)
  Accession Number: 422286
Construct and Test Recombinant Adenoviruses Vectoring African Swine Fever Virus Genes in Inducing Immune Protection in Pigs.
Reimbursable (R)
  Accession Number: 429185
Analysis of the Role of African Swine Fever Virus Proteins in Virus Virulence
Specific Cooperative Agreement (S)
  Accession Number: 428214
Improvement of Interferon Biotherapeutics for Foot-and-Mouth Disease in Swine
Trust (T)
  Accession Number: 427808

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Transcriptomic analysis of persistent infection with foot-and-mouth disease virus in cattle suggests impairment of cell-mediated immunity in the nasopharynx -
Depletion of elongation initiation factor 4E binding proteins by CRISPR/Cas9 genome editing enhances antiviral response in porcine cells -
Ramirez-Carvajal, L., Singh, N., De Los Santos, T.B., Rodriguez, L.L., Zhu, J.J., Long, C.R. 2015. Depletion of elongation initiation factor 4E binding proteins by CRISPR/Cas9 genome editing enhances antiviral response in porcine cells. Antiviral Research. 125:8-13. doi: 10.1016/j.antiviral.2015.11.002.
Treatment with interferon-alpha delays disease in swine infected with a highly virulent CSFV strain Reprint Icon -
Fernandez-Sainz, I., Zhu, J.J., O'Donnell, V., Diaz San Segundo, F.C., Velazquez, L., De Los Santos, T.B., Borca, M.V. 2015. Treatment with interferon-alpha delays disease in swine infected with a highly virulent CSFV strain. Virology. 483:284-290. DOI: 10.1016/j.virol.2015.04.024.
A colorimetric bioassay for high-througput and cost-effectively assessing anti-foot-and-mouth disease virus activity -
Ramanathan, P., Puckette, M., Hartwig, E.J., Bishop, E.A., Rodriguez, L.L., Grubman, M.J., Zhu, J.J. 2015. A colorimetric bioassay for high-througput and cost-effectively assessing anti-foot-and-mouth disease virus activity. Veterinary Immunology and Immunopathology. 164(1-2):74-78. DOI: 0.1016/j.vetimm.2015.01.005.
Expression of porcine fusion protein IRF7/3(5D) efficiently controls foot-and-mouth disease virus replication -
Ramirez-Carvajal, L., Long, C.R., Zhu, J.J., Diaz San Segundo, F.C., Rodriguez, L.L., De Los Santos, T.B. 2014. Expression of porcine fusion protein IRF7/3(5D) efficiently controls foot-and-mouth disease virus replication. Journal of Virology. 88(19):11140-11153.
Mechanisms of foot-and-mouth disease virus tropism inferred from differential tissue gene expression Reprint Icon -
Zhu, J.J., Arzt, J., Puckette, M.C., Smoliga, G.R., Pacheco Tobin, J., Rodriguez, L.L. 2013. Mechanisms of foot-and-mouth disease virus tropism inferred from differential tissue gene expression. PLoS One. 8(5):e64119. DOI:10.1371/journal.pone.0064119.
Antiviral activity of bovine type III interferon against foot-and-mouth disease virus -
Diaz-San Segundo, F., Weiss, M., Perez-Martin, E., Koster, M.J., Zhu, J.J., Grubman, M.J., De Los Santos, T.B. 2011. Antiviral activity of bovine type III interferon against foot-and-mouth disease virus. Virology. 413(2):283-292.
Differential gene expression in bovine cells infected with wild type and leaderless foot-and-mouth disease virus -
Zhu, J.J., Weiss, M., Grubman, M.J., De Los Santos, T.B. 2010. Differential gene expression in bovine cells infected with wild type and leaderless foot-and-mouth disease virus. Virology. 404(1):32-40.
IgA antibody response of swine to foot-and-mouth disease virus infection and vaccination Reprint Icon -
Pacheco Tobin, J., Butler, J.E., Jew, J., Ferman, G., Zhu, J.J., Golde, W.T. 2010. IgA antibody response of swine to foot-and-mouth disease virus infection and vaccination. Clinical and Vaccine Immunology. p. 550-558.
IgA antibody response of swine to foot-and-mouth disease virus (FMDV) infection and vaccination -
Pacheco Tobin, J., Butler, J.E., Jew, J., Ferman, G.S., Zhu, J.J., Golde, W.T. 2010. IgA antibody response of swine to foot-and-mouth disease virus (FMDV) infection and vaccination. Clinical and Vaccine Immunology. 17(4):550-558.
Mutations in the classical swine fever virus NS4B protein affects virulence in swine -
Fernandez Sainz, I., Gladue, D.P., Holinka-Patterson, L.G., O'Donnell, V.K., Gudmundsdottir, I., Prarat, M.V., Patch, J.R., Golde, W.T., Zhiqiang, L., Risatti, G.R., Zhu, J.J., Borca, M.V. 2009. Mutations in the classical swine fever virus NS4B protein affects virulence in swine. Proceedings. P. 143.
Mutations in classical swine fever virus NS4B affect virulence in swine -
Fernandez-Sainz, I., Gladue, D.P., Holinka-Patterson, L.G., O'Donnell, V.K., Gudmundsdottir, I., Prarat, M.V., Patch, J.R., Golde, W.T., Lu, Z., Risatti, G.R., Zhu, J.J., Borca, M.V. 2010. Mutations in classical swine fever virus NS4B affect virulence in swine. Journal of Virology. 84(3):1536-1549.
The region between the two polyprotein initiation codons of foot-and-mouth disease virus is critical for virulence in cattle -
Piccone, M.E., Pacheco Tobin, J., Pauszek, S.J., Borca, M.V., Rieder, A.E., Kramer Jr, E.V., Zhu, J.J., Rodriguez, L.L. 2010. The region between the two polyprotein initiation codons of foot-and-mouth disease virus is critical for virulence in cattle. Virology. 396:152-159.
Functional genomics approach to understand the role of Lpro in FMDV virulence -
De Los Santos, T.B., Grubman, M.J., Zhu, J.J. 2009. Functional genomics approach to understand the role of Lpro in FMDV virulence. American Society for Virology Meeting. Paper No. 9-21: P.262.
A Conserved Domain in the Leader Proteinase of Foot-and-Mouth Disease Virus is Required for Proper Sub-Cellular Localization and Function -
De Los Santos, T.B., Diaz-San Segundo, F., Zhu, J.J., Koster, M.J., Dias, C., Grubman, M.J. 2008. A Conserved Domain in the Leader Proteinase of Foot-and-Mouth Disease Virus is Required for Proper Sub-Cellular Localization and Function. Journal of Virology. 83(4):1800-1810.
Patterns of gene expression in swine macrophages infected with classical swine fever virus detected by microarray -
Gladue, D.P., Zhu, J.J., Holinka-Patterson, L.G., Fernandez-Sainz, I., Prarat, M.V., O'Donnell, V.K., Borca, M.V. 2010. Patterns of gene expression in swine macrophages infected with classical swine fever virus detected by microarray. Virology. 138(1-2):89-96.
Cellular Changes Induced by Adenovirus Vaccine Vectors Expressing Foot-and-Mouth Disease Virus Structural and Nonstructural Proteins -
Moraes, M., O'Donnell, V.K., Burrage, T.G., Pena, L., Diaz-San Segundo, F., Koster, M.J., Zhu, J., Grubman, M.J. 2008. Cellular Changes Induced by Adenovirus Vaccine Vectors Expressing Foot-and-Mouth Disease Virus Structural and Nonstructural Proteins. European Study Group on the Molecular Biology of Picornaviruses. P 203
A Conserved Domain in the Leader Proteinase of Foot-and-Mouth Disease Virus is Required for Proper Subcellular Localization and Function -
De Los Santos, T., San Segundo-Diaz, F., Zhu, J., Koster, M.J., Grubman, M.J. 2008. A conserved domain in the leader proteinase of foot-and-mouth disease virus is required for proper subcellular localization and function. European Study Group on the Molecular Biology of Picornaviruses. P 86
DNA microarray analysis reveals crosstalk of Salmonella enterica serovar Typhimurium with AI-2 of Escherichia coli -
Jesudhasan, P.R., Cepeda, M.L., Widmer, K., Dowd, S.E., Soni, K.A., Hume, M.E., Zhu, J., Pillai, S.D. 2007. DNA microarray analysis reveals crosstalk of Salmonella enterica serovar Typhimurium with AI-2 of Escherichia coli [abstract]. In: American Society for Microbiology Cell to Cell Communication in Bacteria Abstracts, October 7-10, 2007, Austin, Texas. No. 110A.
Gene regulation of Salmonella enterica serovar Typhimurium as influenced by LuxS/AI-2 -
Jesudhasan, P.R., Cepeda, M.L., Widmer, K., Dowd, S.E., Soni, K.A., Hume, M.E., Zhu, J., Pillai, S.D. 2007. Gene regulation of Salmonella enterica serovar Typhimurium as influenced by LuxS/AI-2 [abstract]. American Society for Microbiology Cell to Cell Communication in Bacteria Abstracts, October 7-10, 2007, Austin, Texas. No. 111B.
Autoinducer-2 controls virulence of Salmonella enterica serovar Typhimurium -
Jesudhasan, P.R., Cepeda, M.L., Widmer, K., Dowd, S.E., Soni, K.A., Hume, M.E., Zhu, J., Pillai, S.D. 2007. Autoinducer-2 controls virulence of Salmonella enterica serovar Typhimurium [abstract]. American Society for Microbiology Cell to Cell Communication in Bacteria Abstracts, October 7-10, 2007, Austin, Texas. No. 108A.
Mutations in the Carboxyl Terminal Region of E2 Glycoprotein of Classical Swine Fever Virus are Responsible for Viral Attenuation in Swine -
Risatti, G.R., Holinka, L.G., Fernanez-Sainz, I., Carrillo, C., Kutish, G., Lu, Z., Zhu, J., Rock, D.L., Borca, M.V., 2007, Mutations in the Carboxyl Terminal Region of E2 Glycoprotein of Classical Swine Fever Virus are Responsible for Viral Attenuation in Swine. Positive Strand RNA Virus International Conference Proceedings. P2-K27, p.116
Mutations in the Carboxyl Terminal Region of E2 Glycoprotein of Classical Swine Fever Virus is Responsible for Viral Attenuation in Swine -
Risatti, G., Holinka, L.G., Fernandez-Sainz, I., Carrillo, C., Kutish, G.F., Lu, Z., Zhu, J., Rock, D.L., Borca, M.V. 2007. Mutations in the Carboxyl Terminal Region of E2 Glycoprotein of Classical Swine Fever Virus is Responsible for Viral Attenuation in Swine. Virology. 364 (2): 371-82.
Genomics and vaccine development -
Gay, C.G., Zuerner, R., Bannantine, J.P., Lillehoj, H.S., Zhu, J., Green, R.D., Pastoret, P.P. 2007. Genomics and vaccine development. OIE Rev. Sci Tech. 26:49-67.
GENE EXPRESSION PROFILING TO STUDY 12 CYTOKINE PRODUCTION AFTER EIMERIA INFECTION -
MAPPING QUANTITATIVE TRAIT LOCI AFFECTING DISEASE RESISTANCE TO AVIAN COCCIDIOSIS (73RD NECAB MTG, COLLEGE PARK, MD) -
MAPPING QTL LOCI AFFECTING GROWTH AND DISEASE RESISTANCE TO AVIAN COCCIDIOSIS -
ANALYSIS OF DISEASE RESISTANCE ASSOCIATED PARAMETERS IN BROILER CHICKENS -
KINETIC DIFFERENCES IN INTESTINAL AND SYSTEMIC INFERFERON-GAMMA AND ANTIGEN-SPECIFIC ANTIBODIES IN CHICKENS EXPERIMENTALLY INFECTED WITH EIMERIA MAXIMA -
KINETIC DIFFERENCES IN INTESTINAL AND SYSTEMIC INTERFON-GAMMA AND ANTIGEN- SPECIFIC ANTIBODIES IN CHICKENS EXPERIMENTALLY INFECTED WITH EIMERIA MAXIMA -
ANALYSIS OF DISEASE RESISTANCE ASSOCIATED PARAMETERS. ANALYSIS OF DISEASE RESISTANCE ASSOCIATED PARAMETERS IN BROILER CHICKENS CHALLENGED WITH EIMERIA MAXIMA -
MAREK'S DISEASE CHALLENGE OF AN F2 BROILER CHICKEN POPULATION -
KINETIC DIFFERENCES IN INTESTINAL AND SYSTEMIC INFERTERON-GAMMA AND ANTIGEN-SPECIFIC ANTIBODIES IN CHCKENS EXPERIMENTALLY INFECTED WITH EIMERIAMAXIMA -
SCREENING FOR HETEROZYGOUS CHICKENS. SCREENING FOR HIGHLY HETEROZYGOUS CHICKENS IN OUTBRED COMMERCIAL BROILER LINES TO INCREASE DETECTION POWER FOR MAPPING QUANTITATIVE TRAIT LOCI -
SCREENING FOR HIGHLY HETEROZYGOUS CHICKENS IN OUTBRED COMMERCIAL BROILER LINES TO INCREASE DETECTION POWER FOR MAPPING QUANTITATIVE TRAIT LOCI -
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Last Modified: 5/2/2016
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