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ARS Home » Plains Area » Lubbock, Texas » Cropping Systems Research Laboratory » Livestock Issues Research » Research » Publications at this Location » Publication #412922

Research Project: Environmental and Management Influences on Animal Productivity and Well-Being Phenotypes

Location: Livestock Issues Research

Title: Evaluating the effects of acidosis and bacterial concentrations on the development of liver abscesses in beef steers

item CHILDRESS, KALLIE - Texas Tech University
item HALES, KRISTIN - Texas Tech University
item NAGARAJA, T - Kansas State University
item LAWRENCE, TY - West Texas A & M University
item AMACHAWADI, RAGHAVENDRA - Kansas State University
item Sanchez, Nicole
item MCDANIEL, ZACH - Texas Tech University
item LINE, DALTON - Texas Tech University
item THOMPSON-SMITH, AUBREY - Texas Tech University
item HANRATTY, ASHLEY - Texas Tech University
item SHI, XIARONG - Kansas State University
item ABBASI, MINA - Kansas State University
item GALYEAN, MICHAEL - Texas Tech University
item BALLOU, MICHAEL - Texas Tech University
item MACHADO, VINICIUS - Texas Tech University
item Broadway, Paul

Submitted to: Proceeding of Plains Nutrition Council Symposium
Publication Type: Abstract Only
Publication Acceptance Date: 3/1/2024
Publication Date: N/A
Citation: N/A

Interpretive Summary:

Technical Abstract: We evaluated the association of diet type, ruminal acidosis bout frequency, and intraruminal bacterial inoculum concentration upon liver abscess (LA) development in cattle. Beef x dairy steers (n = 40, initial BW = 236 +/- 24 lb) were assigned randomly to 1 of 5 treatments that included either a high-dose (HD; 1x10^9 and 1x10^9 CFU/mL) or a low-dose (LD; 1x10^6 and 1x10^6 CFU/mL) of Fusobacterium necrophorum subsp. necrophorum and Salmonella enterica, respectively. Treatments included: NCON = high-forage diet with no intraruminal inoculation; CON+HD = high-forage diet with a single, HD inoculation; 2AD+HD = 2 acidotic diet cycles with a single, HD inoculation; 4AD+3LD = 4 acidotic diet cycles with a series of 3 LD inoculations; and 4AD+HD = 4 acidotic diet cycles with a single, HD inoculation. Individual animal was the experimental unit. Continuous data were analyzed using mixed models, and categorical data were analyzed as binomial proportions with treatment, time, and their interactions as the fixed effects. Hematology was evaluated before harvest on d 21 to investigate systemic disease; minimal differences were observed in hematology. Although no difference was observed in ruminal damage among treatments (P = 0.79), steers with LA presented with 8 percentage points greater ruminal damage than steers without LA. Steers consuming only high-forage diet treatments also presented with rumenitis. Prevalence of LA was 0, 37.5, 37.5, 50, and 12.5% for NCON, CON+HD, 2AD+HD, 4AD+3LD, and 4AD+HD, respectively (P = 0.68). A key observation of this study was that steers fed a high-forage diet presented with LA when dosed with F. necrophorum and S. enterica, even in the absence of the acidotic diet.