Location: National Cold Water Marine Aquaculture Center
Title: THE ROLE OF MITOCHONDRIAL AND LYSOSOMAL PERMEABILIZATION IN EASTERN OYSTER APOPTOTIC RESPONSE TO PERKINSUS MARINUSAuthor
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PURITZ, JON - University Of Rhode Island |
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ZHAO, HONGGANG - Cornell University |
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WEEDOP, BODIE - Northeastern University |
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MODAK, TEJASHREE - University Of Rhode Island |
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ROBERTS, ERIN - University Of Rhode Island |
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ALLEN, STAN - Virginia Institute Of Marine Science |
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HARE, MATT - Cornell University |
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LOTTERHOS, KATIE - Northeastern University |
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RAWSON, PAUL - University Of Maine |
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SCHWARTZ, RACHEL - University Of Rhode Island |
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Proestou, Dina |
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GUO, XIMING - Rutgers University |
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WARREN, WES - University Of Missouri |
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GOMEZ-CHIARRI, MARTA - University Of Rhode Island |
Submitted to: Meeting Abstract
Publication Type: Abstract Only Publication Acceptance Date: 12/7/2020 Publication Date: N/A Citation: N/A Interpretive Summary: N/A Technical Abstract: Genetic variation in the eastern oyster has been studied for over half a century with questions relating to adaptation, disease tolerance, population structure, sweepstakes reproduction and much more. Interest has been sustained because of this species’ commercial importance, the desire to supplement populations for fisheries or restoration purposes, and with basic research questions. Many of these endeavors were limited by the genetic resources available. The chromosome-scale reference genome assembly for C. virginica, described in this talk, represents a turning point. Metrics indicating robustness of the assembly and some basic genome structure findings will be described before focusing on geographic population structure and selected strain divergence as examples where genome-scale analysis of diversity provides new insights. Samples from Maine to Texas, along with five of the major selected strains, were subjected to whole genome re-sequencing. The overwhelming and genomically pervasive pattern is divergence between Atlantic and Gulf of Mexico (GoM) regions, recapitulating previous inferences from lower resolution mitochondrial and nuclear marker studies. High genetic diversity has been maintained in all selected strains examined, and their divergence from source stocks is modest relative to the Atlantic - GoM divide. Evidence of selection affecting specific loci was most convincing in high and low salinity contrasts within estuaries, where background noise from genetic drift was likely reduced by high gene flow. |