Location: Foreign Disease-Weed Science ResearchTitle: Viral hacks of the plant vasculature: the role of phloem alterations in systemic virus infection
|KAPPAGANTU, MADHU - University Of Maryland|
|Collum, Tamara - Tami|
|Dardick, Christopher - Chris|
|CULVER, JAMES - University Of Maryland|
Submitted to: Annual Review of Virology
Publication Type: Review Article
Publication Acceptance Date: 2/5/2020
Publication Date: 5/26/2020
Citation: Kappagantu, M., Collum, T.D., Dardick, C.D., Culver, J.N. 2020. Viral hacks of the plant vasculature: the role of phloem alterations in systemic virus infection. Annual Review of Virology. 7:10.1-10.20. https://doi.org/10.1146/annurev-virology-010320-072410.
Technical Abstract: For plant viruses, the ability to load into the vascular phloem and spread systemically within a host is an essential step in establishing a successful infection. However, access to the vascular phloem is a highly regulated, representing a significant obstacle to virus loading, movement and subsequent unloading into distal uninfected tissues. Recent studies indicate that during virus infection phloem tissues are a source of significant transcriptional and translational alterations with the number of virus induced differentially expressed genes being four to six-fold greater in phloem tissues than in non-phloem tissues. In addition, viruses target phloem specific components as a means to promote their own systemic movement and disrupt host defense processes. Combined these studies provide evidence that the vascular phloem plays a significant role in the mediation and control of host responses during infection and as such are a site of considerably modulation by the infecting virus. This review outlines the vascular phloem responses and directed reprograming mechanisms that viruses employ to promote their movement through the vasculature.