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ARS Home » Northeast Area » Frederick, Maryland » Foreign Disease-Weed Science Research » Research » Publications at this Location » Publication #371235

Research Project: Molecular Identification, Characterization, and Biology of Foreign and Emerging Viral and Bacterial Plant Pathogens

Location: Foreign Disease-Weed Science Research

Title: Viral hacks of the plant vasculature: the role of phloem alterations in systemic virus infection

Author
item KAPPAGANTU, MADHU - University Of Maryland
item Collum, Tami
item Dardick, Christopher - Chris
item CULVER, JAMES - University Of Maryland

Submitted to: Annual Review of Virology
Publication Type: Review Article
Publication Acceptance Date: 2/5/2020
Publication Date: 5/26/2020
Citation: Kappagantu, M., Collum, T.D., Dardick, C.D., Culver, J.N. 2020. Viral hacks of the plant vasculature: the role of phloem alterations in systemic virus infection. Annual Review of Virology. 7:10.1-10.20. https://doi.org/10.1146/annurev-virology-010320-072410.
DOI: https://doi.org/10.1146/annurev-virology-010320-072410

Interpretive Summary:

Technical Abstract: For plant viruses, the ability to load into the vascular phloem and spread systemically within a host is an essential step in establishing a successful infection. However, access to the vascular phloem is a highly regulated, representing a significant obstacle to virus loading, movement and subsequent unloading into distal uninfected tissues. Recent studies indicate that during virus infection phloem tissues are a source of significant transcriptional and translational alterations with the number of virus induced differentially expressed genes being four to six-fold greater in phloem tissues than in non-phloem tissues. In addition, viruses target phloem specific components as a means to promote their own systemic movement and disrupt host defense processes. Combined these studies provide evidence that the vascular phloem plays a significant role in the mediation and control of host responses during infection and as such are a site of considerably modulation by the infecting virus. This review outlines the vascular phloem responses and directed reprograming mechanisms that viruses employ to promote their movement through the vasculature.