Location: Animal Parasitic Diseases LaboratoryTitle: Coccidiosis in humans – the past 100 years: A revision of the Coccidia Parasitic in man
Submitted to: Parasitology
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 7/29/2019
Publication Date: 7/29/2019
Citation: Dubey, J.P. 2019. Coccidiosis in humans – the past 100 years: A revision of the Coccidia Parasitic in man. Parasitology. 11(2):147-197. https://doi.org/10.1017/S0031182000004170.
Interpretive Summary: Toxoplasma, Neospora, Sarcocystis, and Cystoisopora are related coccidian parasites that cause severe illness in livestock and companion animals. Oocyst is the environmentally resistant stage passed in feces of the definitive hosts. While Toxoplasma and Neospora have wide host range, Cystoisospora are more host specific. Cystoisospora belli is a pathogenic coccidian of humans. Its life cycle is not fully known. Recently, an ARS researcher, Dubey, in collaboration with medical pathologists described asexual and sexual cycle of C. belli in biopsy specimens of small intestine of one and the common bile duct of another patient. The development of C. belli was found to be like the development of intestinal stages of Cystoisospora species from dogs and cats. In the present invited editorial, Dubey summarizes progress made in understanding of coccidia of humans for the past 100 years. This review will be of interest to parasitologists and biologists.
Technical Abstract: This paper reviews history of human coccidia for the past century.