Submitted to: National Center for Biotechnology Information (NCBI)
Publication Type: Other
Publication Acceptance Date: 4/25/2016
Publication Date: N/A
Interpretive Summary: A single nucleotide polymorphism, or SNP, is a single base change in the DNA sequence that occurs in a significant proportion (<1 percent) of a large population. SNPs are a source of variation within a genome that is conserved across the genome and, as such, can be correlated with a particular trait, such as disease resistance or growth rate. Animals can be genotyped for thousands of SNPs to predict and/or identify desirable or undesirable traits. The Axiom®Turkey Genotyping Array is a new genetic tool that will enable turkey breeders to screen individual birds for traits of economic importance that are not otherwise easily measured.
Technical Abstract: The Axiom®Turkey Genotyping Array interrogates 643,845 probesets on the array, covering 643,845 SNPs. The array development was led by Dr. Julie Long of the USDA-ARS Beltsville Agricultural Research Center under a public-private partnership with Hendrix Genetics, Aviagen, and Affymetrix. The Turkey Genome Sequencing Consortium led the efforts to sequence the turkey genome. The SNP marker discovery effort was led by Prof. Martien Groenen of the Animal Breeding and Genomics Centre at Wageningen University in the Netherlands, and was funded by USDA’s National Institute of Food and Agriculture. The SNP markers on the turkey array were selected by Dr. Curt Van Tassell of the USDA-ARS Beltsville Agricultural Research Center.