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ARS Home » Northeast Area » Beltsville, Maryland (BARC) » Beltsville Agricultural Research Center » Animal Biosciences & Biotechnology Laboratory » Research » Publications at this Location » Publication #326948

Research Project: Functional Genomics Approaches for Controlling Diseases of Poultry

Location: Animal Biosciences & Biotechnology Laboratory

Title: Evaluation of the in vitro effects of Allium hookeri on broiler chicken lymphocytes, macrophages and tumor cells

Author
item Lillehoj, Hyun
item LEE, YOUNGSUB - US Department Of Agriculture (USDA)

Submitted to: Poultry Science Association Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 4/10/2016
Publication Date: N/A
Citation: N/A

Interpretive Summary:

Technical Abstract: Large members of Allium species have been widely used around Asia as food or as traditional medicinal plants that prevent infection. Allium hookeri has also been reported to have antimicrobial activities. The objective of this study was to investigate the effect of ethanol extracts of A. hookeri (leaf, root, and fermented root) on various in vitro parameters of innate immunity (spleen lymphocyte proliferation) as well as the suppression of tumor cells growth. Additionally, the investigation also evaluated the antioxidant effect (free radical scavenging activity). The ethanol extracts from the three powders stimulated lymphocyte proliferation, induced nitric oxide production and suspended tumor cell growth when compared with the media negative control. Also, potent scavenging capacity showed by DPPH assay. These results suggest that the ethanol extract of A. hookeri can be used as a potential alternative to enhance innate immune of the poultry.