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ARS Home » Northeast Area » Beltsville, Maryland (BARC) » Beltsville Agricultural Research Center » Animal Biosciences & Biotechnology Laboratory » Research » Publications at this Location » Publication #301485

Title: The gut immune system: A new frontier in gut health research

item Lillehoj, Hyun

Submitted to: Australian Poultry Science Symposium
Publication Type: Abstract Only
Publication Acceptance Date: 1/11/2014
Publication Date: 2/16/2014
Citation: Lillehoj, H.S. 2014. The gut immune system: A new frontier in gut health research. Australian Poultry Science Symposium. CD.

Interpretive Summary:

Technical Abstract: As the world population grows and developing countries become more affluent, the global consumption of meat will increase by more than 50% within the next 10 years. Confronting the increasing demand for poultry food products are emerging field diseases, increasing regulatory ban of antibiotics growth promoters (AGPs), high-density growth conditions, and waste management. A new paradigm is needed to develop a sustainable poultry production system in view of growing challenges in managing the complex ecosystem that controls poultry production. In this presentation, a new understanding on the role of host immunity in controlling cross talk among nutrient, gut microbiota, neuroendocrine and epigenetic systems will be discussed. There is also increasing scientific evidence that implicates the negative consequences of dietary antibiotics on gut microflora, local innate immunity, disease resistance, and overall animal well being. This presentation will highlight some emerging strategies to enhance gut immunity and to decrease economic losses due to poultry diseases such as coccidiosis and necrotic enteritis. Such information will magnify our understanding of host-parasite biology, mucosal immunology, and facilitate the design of future dietary interventions and vaccination strategies to reduce economic losses due to coccidiosis and necrotic enteritis.