Submitted to: International Cotton Genome Initiative Workshop
Publication Type: Abstract Only
Publication Acceptance Date: 8/18/2006
Publication Date: 9/18/2006
Citation: Abdurakhomonov, I.Y., Kohel, R.J., Saha, S., Pepper, A.E., Yu, J., Buriev, Z.T., Shermatov, S.E., Abdullaev, A.A., Kushanov, F.N., Jenkins, J.N., Scheffler, B.E., Abdukarimov, A. 2006. Linkage disequilibrium based association mapping of fiber quality traits in cotton using diverse cotton germplasm from Uzbekistan [abstract]. In: Proceedings of International Cotton Genome Initiative Workshop, Structural Genomics Session, September 18-20, 2006, Brasilia, Brazil. Paper No. 7. Available: http://icgi.tamu.edu/pdf/icgi06_abs_final.pdf.
Technical Abstract: QTL-mapping, a now-classical approach to identify molecular markers linked to complex traits in specific experimental populations, is extremely time-consuming, high-risk, and expensive work - prohibitively expensive if dozens, let alone hundreds or thousands, of germplasm accessions are to be examined. However, use of linkage disequilibrium (LD) based association mapping circumvents the need for large F2 or RI mapping populations by making use of information contained within the genetic recombinations that have occurred in cotton genome during the course of recent evolution. By this method, certain alleles at a marker locus can be associated with alleles at a linked locus affecting a trait of interest. LD mapping permits much finer-scale mapping than does QTL-mapping.