Location: Virus and Prion Research
Project Number: 5030-32000-119-13-N
Project Type: Non-Funded Cooperative Agreement
Start Date: Jan 15, 2019
End Date: Jan 14, 2021
The goal of this collaboration is to examine the survival of the animal pathogen Bordetella bronchiseptica in aerosols and to identify bacterial genes and responses that contribute to survival.
1) Determine the optimal time for evaluation of aerosol stress for B. bronchiseptica; 2) Determine transcriptional response during aerosolization for B. bronchiseptica (RNASeq); 3) Identify B. bronchiseptica genes required for persistence in aerosols; and 4) Determine if specific gene products (identified in studies two and three) are necessary or aid in survival during nebulization or aerosolization stress for B. bronchiseptica.