Location: Animal Disease Research
Project Number: 2090-32000-039-20-T
Project Type: Trust Fund Cooperative Agreement
Start Date: Feb 1, 2018
End Date: Jul 1, 2020
Developing a recombinant dual vaccine against Babesia bovis able to prevent both, acute disease and parasite transmission in endemic areas, practical to be used in neglected endemic regions worldwide.
We propose developing the following two specific aims: SA#1] Developing bioinformatics and experimental platforms for the identification and in vitro testing of antigens to be components of a cyto-adhesion and transmission blocking vaccine against B. bovis. SA#2] Testing subunit vaccines aimed at preventing acute babesiosis and transmission of B. bovis in cattle, based on the antigens selected in SA#1.