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ARS Home » Pacific West Area » Pullman, Washington » Animal Disease Research » People & Locations » David Herndon

David R Herndon
Animal Disease Research
Molecular Biologist

Phone: (509) 335-6004
Fax: (509) 335-8328

3047 ADBF, WSU
PULLMAN, WA 991646630
Projects
Genetic Impact and Improved Diagnostics for Sheep and Goat Transmissible Spongiform Encephalopathies
In-House Appropriated (D)
  Accession Number: 431730
Identification of Host Factors and Immunopathogenesis of Pneumonia in Domestic and Bighorn Sheep
In-House Appropriated (D)
  Accession Number: 431731
Identification of Tick Colonization Mechanisms and Vaccine Development for Anaplasmosis
In-House Appropriated (D)
  Accession Number: 431740

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Mycoplasma ovis infection in domestic sheep (Ovis aries) in the United States: prevalence, distribution, associated risk factors, and associated outcomes Reprint Icon - (Peer Reviewed Journal)
Urie, N.J., Highland, M.A., Knowles, D.P., Brannan, M.A., Herndon, D.R., Marshall, K.L. 2019. Mycoplasma ovis infection in domestic sheep (Ovis aries) in the United States: prevalence, distribution, associated risk factors, and associated outcomes. Preventive Veterinary Medicine. 171. https://doi.org/10.1016/j.prevetmed.2019.104750.
A recombinant bovine herpesvirus-4 vectored vaccine delivered via intranasal nebulization elicits viral neutralizing antibody titers in cattle Reprint Icon - (Peer Reviewed Journal)
Williams, L.B., Fry, L.M., Herndon, D.R., Franceschi, V., Schneider, D.A., Donofrio, G., Knowles, D.P. 2019. A recombinant bovine herpesvirus-4 vectored vaccine delivered via intranasal nebulization elicits viral neutralizing antibody titers in cattle. PLoS One. 14(4):e0215605. https://doi.org/10.1371/journal.pone.0215605.
Identification of Mycoplasma ovipneumoniae in wildlife species beyond the subfamily caprinae Reprint Icon - (Peer Reviewed Journal)
Highland, M.A., Herndon, D.R., Bender, S., Hansen, L., Gerlach, R.F., Beckman, K.B. 2018. Identification of Mycoplasma ovipneumoniae in wildlife species beyond the subfamily caprinae. Emerging Infectious Diseases. 24(12):2384-2386. https://doi.org/10.3201/eid2412.180632.
Discovery of a novel species Theileria haneyi n. sp. infective to equids highlights exceptional genomic diversity within the genus Theileria: implications for apicomplexan parasite surveillance Reprint Icon - (Peer Reviewed Journal)
Knowles, D.P., Kappmeyer, L.S., Haney, D., Herndon, D.R., Fry, L.M., Munro, J.B., Sears, K., Ueti, M.W., Wise, L.N., Silva, M., Schneider, D.A., Grause, J., White, S.N., Trentina, K., Bishop, R., Odongo, D.O., Pelzel-McCluske, A.M., Scoles, G.A., Mealey, R.H., Silva, J.C. 2018. Discovery of a novel species Theileria haneyi n. sp. infective to equids highlights exceptional genomic diversity within the genus Theileria: implications for apicomplexan parasite surveillance. International Journal for Parasitology. 48(9-10):127-137. https://doi.org/10.1016/j.ijpara.2018.03.010.
The babesia bovis hap2 gene is not required for blood stage replication, but expressed upon in vitro sexual stage induction Reprint Icon - (Peer Reviewed Journal)
Hussein, H.E., Bastos, R.G., Schneider, D.A., Johnson, W.C., Adham, F.K., Davis, W.C., Laughery, J.M., Herndon, D.R., Alzan, H.F., Ueti, M.W., Suarez, C.E. 2017. The babesia bovis hap2 gene is not required for blood stage replication, but expressed upon in vitro sexual stage induction. PLOS Neglected Tropical Diseases. 11(10):e0005965. https://doi.org/10.1371/journal.pntd.0005965.
Geno- and phenotypic characteristics of a transfected babesia bovis 6-Cys-E knockout clonal line - (Peer Reviewed Journal)
Alzan, A., Silva, M., Davis, W., Herndon, D.R., Schneider, D.A., Suarez, C.E. 2017. Geno- and phenotypic characteristics of a transfected babesia bovis 6-Cys-E knockout clonal line. Parasites & Vectors. 10(1):214.
Expression of 6-Cys gene superfamily defines babesia bovis sexual stage development within rhipicephalus microplus - (Peer Reviewed Journal)
Alzan, H.F., Lau, A., Knowles, D.P., Herndon, D.R., Ueti, M.W., Scoles, G.A., Kappmeyer, L.S., Suarez, C.E. 2016. Expression of 6-Cys gene superfamily defines babesia bovis sexual stage development within rhipicephalus microplus. PLoS One. doi:10.1371/journal.pone.0163791.
Ovine leukocyte profiles do not associate with variation in the prion gene, but are breed-dependent - (Peer Reviewed Journal)
Mousel, M.R., White, S.N., Herndon, D.R., Reynolds, J.O., Gonzalez, M., Johnson, W.C., Ueti, M.W., Taylor, J.B., Knowles Jr, D.P. 2015. Ovine leukocyte profiles do not associate with variation in the prion gene, but are breed-dependent. Animal Genetics. 47(1):136-37.
Anaplasma marginale superinfection attributable to pathogen strains with distinct genomic backgrounds. - (Peer Reviewed Journal)
Vallejo, E., Herndon, D.R., Mendoza, F., Mosqueda, J., Palmer, G. 2014. Anaplasma marginale superinfection attributable to pathogen strains with distinct genomic backgrounds. Infection and Immunity. 82(12):5286-5292.
Malignant catarrhal fever in American bison (Bison bison) experimentally infected with alcelaphine herpesvirus 2 - (Peer Reviewed Journal)
Taus, N.S., O'Toole, D., Herndon, D.R., Cunha, C.W., Warg, J.V., Seal, B.S., Brooking, A., Li, H. 2014. Malignant catarrhal fever in American bison (Bison bison) experimentally infected with alcelaphine herpesvirus 2. Veterinary Microbiology. DOI:10.1016/j.vetmic.2014.04.003.
A divergent artiodactyl MYADM-like repeat is associated with erythrocyte traits and weight of lamb weaned in domestic sheep - (Peer Reviewed Journal)
Gonzalez, M.V., Mousel, M.R., Herndon, D.R., Jiang, Y., Dalrymple, B.P., Reynolds, J.O., Johnson, W.C., Herrmann-Hoesing, L.M., White, S.N. 2013. A divergent artiodactyl MYADM-like repeat is associated with erythrocyte traits and weight of lamb weaned in domestic sheep. PLoS One. 8(8):e74700. doi: 10.1371/journal.pone.0074700.
Identification of multi-locus genetic heterogeneity in anaplasma marginale ss. centrale and its restriction following tick-borne transmission. Reprint Icon - (Peer Reviewed Journal)
Herndon, D.R., Ueti, M.W., Reif, K.E., Noh, S.M., Brayton, K.A., Agnes, J.T., Palmer, G.H. 2013. Identification of multi-locus genetic heterogeneity in anaplasma marginale ss. centrale and its restriction following tick-borne transmission. Infection and Immunity. 81(5):1852-8.
Comparative genomic analysis and phylogenetic position of Theileria equi Reprint Icon - (Peer Reviewed Journal)
Kappmeyer, L.S., Thiagarajan, M., Herndon, D.R., Ramsay, J.D., Caler, E., Djikeng, A., Gillespie, J.J., Lau, A.O., Roalson, E.H., Silva, J.C. 2012. Comparative genomic analysis and phylogenetic position of Theileria equi. Biomed Central (BMC) Genomics. BMC Genomics 2012, 13:603.
Non-maternal transmission is the major mode of ovine lentivirus transmission in a ewe flock: A molecular epidemiology study - (Peer Reviewed Journal)
Broughton-Neiswanger, L.E., White, S.N., Knowles Jr, D.P., Mousel, M.R., Lewis, G.S., Herndon, D.R., Hoesing, L.M. 2010. Non-maternal transmission is the major mode of ovine lentivirus transmission in a ewe flock: A molecular epidemiology study. Infection, Genetics and Evolution. 10(7):998-1007.
Association of pathogen strain-specific gene transcription and transmission efficiency phenotype of Anaplasma marginale - (Peer Reviewed Journal)
Agnes, J.T., Herndon, D.R., Ueti, M.W., Ramabu, S., Evans, M., Brayton, K.A., Palmer, G.H. 2010. Association of pathogen strain-specific gene transcription and transmission efficiency phenotype of Anaplasma marginale. Infection and Immunity. Available: http://iai.asm.org/cgi/reprint/IAI.00108-10v1
Genome sequences of mannheimia haemolytica serotype A2: ovine and bovine isolates - (Peer Reviewed Journal)
Lawrence, P.K., Kittichotirat, W., Bumgarner, R.E., Mcdermott, J.E., Herndon, D.R., Knowles Jr, D.P., Srikumaran, S. 2010. Genome sequences of mannheimia haemolytica serotype A2: ovine and bovine isolates. Journal of Bacteriology. 192(4):1167-8.
blaCMY-2-positive IncA/C plasmids from escherichia coli and salmonella enterica are a distinct component of a larger lineage of plasmids - (Peer Reviewed Journal)
Call, D.R., Singer, R.S., Meng, D., Broschat, S.L., Orfe, L.H., Anderson, J.M., Herndon, D.R., Kappmeyer, L.S., Daniels, J.B., Besser, T.E. 2010. blaCMY-2-positive IncA/C plasmids from escherichia coli and salmonella enterica are a distinct component of a larger lineage of plasmids. Antimicrobial Agents and Chemotherapy. 54(2):590-6.
Complete Genome Sequence of Anaplasma marginale subsp. centrale - (Peer Reviewed Journal)
Herndon, D.R., Palmer, G.H., Shkap, V., Knowles Jr, D.P., Brayton, K.A. 2010. Complete Genome Sequence of Anaplasma marginale subsp. centrale. Journal of Bacteriology. 192(1):379-380.
Conservation in the face of diversity: multistrain analysis of an intracellular bacterium - (Peer Reviewed Journal)
Dark, M.J., Herndon, D.R., Kappmeyer, L.S., Gonzales, M.P., Nordeen, E., Palmer, G.H., Knowles Jr, D.P., Brayton, K.A. 2009. Conservation in the face of diversity: multistrain analysis of an intracellular bacterium. Biomed Central (BMC) Genomics. 10:16.
Genomic analysis of Ovis aries (Ovar)MHC Class IIa loci - (Peer Reviewed Journal)
Hoesing, L.M., White, S.N., Kappmeyer, L.S., Herndon, D.R., Knowles Jr, D.P. 2008. Genomic analysis of Ovis aries (Ovar)MHC Class IIa loci. Immunogenetics. 60(3):167-176.
Association of Mycoplasma ovipneumoniae Infection with Population-Limiting Respiratory Disease in Free-Ranging Rocky Mountain Bighorn Sheep (Ovis canadensis canadensis) - (Peer Reviewed Journal)
Besser, T.E., Cassirer, K.A., Potter, K.A., Vanderschalie, J., Fischer, A., Knowles Jr, D.P., Herndon, D.R., Rurangirwa, F.R., Weiser, G.C., Srikumaran, S. 2008. Association of Mycoplasma ovipneumoniae Infection with Population-Limiting Respiratory Disease in Free-Ranging Rocky Mountain Bighorn Sheep (Ovis canadensis canadensis). Journal of Clinical Microbiology. 46(2):423-430.
Genome Sequence of Babesia bovis and Camparative Analysis of Apicomplexan Hemoprotozoa - (Peer Reviewed Journal)
Brayton, K., Lau, A.O., Herndon, D.R., Hannick, L., Kappmeyer, L.S., Berens, S.J., Bidwell, S.L., Brown, W.C., Crabtree, J., Fadrosh, D., Feldblum, T., Forberger, H.A., Haas, B.J., Howell, J.M., Khouri, H., Koo, H., Mann, D.J., Norimine, J., Paulsen, I.T., Radune, D., Ren, Q., Smith, R.K., Suarez, C.E., White, O., Wortman, J.R., Knowles Jr, D.P., Mcelwain, T.F., Nene, V.M. 2007. Genome Sequence of Babesia bovis and Camparative Analysis of Apicomplexan Hemoprotozoa. PLoS Pathogens. 3(10):1401-1413.
COMPARISON OF OVINE HERPESVIRUS 2 GENOMES ISOLATED FROM DOMESTIC SHEEP (OVIS ARIES) AND A CLINICALLY AFFECTED COW (BOS BOVIS) - (Peer Reviewed Journal)
Taus, N.S., Herndon, D.R., Traul, D., Stewart, J.P., Ackermann, M., Li, H., Knowles Jr, D.P., Lewis, G.S., Brayton, K.A. 2007. Comparison of ovine herpesvirus 2 genomes isolated from domestic sheep (Ovis aries) and a clinically affected cow (Bos bovis). Journal of General Virology. 88(1):40-45.
A NOVEL 78-KDA FATTY ACYL-COA SYNTHETASE (ACS1) OF BABESIA BOVIS STIMULATES MEMORY CD4+ T LYMPHOCYTE RESPONSES IN B. BOVIS-IMMUNE CATTLE - (Peer Reviewed Journal)
Norimine, J., Ruef, B.J., Palmer, G.H., Knowles Jr, D.P., Herndon, D.R., Rice-Ficht, A.C., Brown, W.C. 2006. A novel 78-kDa fatty acyl-CoA synthetase (ACS1) of Babesia bovis stimulates memory CD4+ T lymphocyte responses in B. bovis-immune cattle. Molecular and Biochemical Parasitology. 147(1):20-29
COMPLETE GENOME SEQUENCING OF ANAPLASMA MARGINALE REVEALS THAT THE SURFACE IS SKEWED TO TWO SUPERFAMILIES OF OUTER MEMBRANE PROTEINS - (Peer Reviewed Journal)
Brayton, K.A., Kappmeyer, L.S., Herndon, D.R., Dark, M.J., Tibbals, D.L., Palmer, G.H., Mcguire, T.C., Knowles Jr, D.P. 2005. Complete genome sequencing of anaplasma marginale reveals that the surface is skewed to two superfamilies of outer membrane proteins. Proceedings of the National Academy of Sciences. 102(3):844-849.