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United States Department of Agriculture

Agricultural Research Service

Research Project: NOVEL TECHNOLOGY FOR RENEWABLE RESOURCE UTILIZATION

Location: Renewable Product Technology Research Unit

Title: Antioxidant efficacy of feruloyl glycerols in model membranes

Authors
item Compton, David
item Evans, Kervin
item Laszlo, Joseph

Submitted to: American Chemical Society Abstracts
Publication Type: Abstract Only
Publication Acceptance Date: September 12, 2013
Publication Date: September 12, 2013
Citation: Compton, D.L., Evans, K.O., Laszlo, J.A. 2013. Antioxidant efficacy of feruloyl glycerols in model membranes. American Chemical Society Abstracts.

Technical Abstract: Ferulic acid and its esters are known to be effective antioxidants. Ethyl ferulate was biocatalytically transesterified with triacylglycerols and long chain alcohols to form a series of lipid-based feruloyl esters: feruloylglycerol, diferuloylglycerol, feruloyldiacylglycerol, diferuloylacylglycerol, and octadecyl ferulate. The feruloylglycerol acted as a rapid antioxidant (50% reduction of DPPH radical < 5 min) in ethanol solutions and diferuloyl glycerol was an intermediate antioxidant (50% reduction of DPPH radical in 5–30 min). Partitioning behavior, bilayer depth, and antioxidant characteristics of the feruloylglycerols were determined in phospholipid vesicles. Each feruloyl glycerol derivative incorporated well into liposomes, proving to be non-destructive to the bilayer. Bilayer depth analysis placed ferulic acid, the feruloylglyceols, and octadecyl ferulate at nearly the same bilayer depth. The feruloylglycerols proved better antioxidants in the liposomes than octadecyl ferulate.

Last Modified: 10/21/2014
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