Page Banner

United States Department of Agriculture

Agricultural Research Service

Research Project: DEVELOPING BIOCONVERSION PROCESSES FOR HIGH-VALUE CARBOHYDRATE PRODUCTS Title: Bifidobacteria: Genomics and Molecular Aspects

Authors
item Sela, David -
item Price, Neil
item Mills, David -

Submitted to: Book Chapter
Publication Type: Book / Chapter
Publication Acceptance Date: July 15, 2010
Publication Date: August 1, 2010
Citation: Sela, D.A., Price, N.P., Mills, D.A. 2010. Bifidobacteria: Genomics and molecular aspects. In: Mayo, B., van Sinderen, D., editors. Bifidobacteria: Genomics and Molecular Aspects, Chapter 4, Norfolk, U.K.: Caister Academic Press. p. 45-70.

Technical Abstract: The genus Bifidobacterium possesses a unique fructose-6-phosphate phosphoketolase pathway employed to ferment carbohydrates. Much metabolic research on bifidobacteria has focused on oligosaccharide metabolism as these carbohydrate polymers are available in their otherwise nutrient-limited habitats. Interestingly, infant-associated bifidobacterial phylotypes appear to have evolved the ability to ferment milk oligosaccharides, whereas adult-associated species utilize plant oligosaccharides, consistent with what they encounter in their respective environments. As breast-fed infants often harbor bifidobacteria dominated gut consortia, there have been numerous applications to mimic the bifidogenic properties of milk oligosaccharides. These are broadly classified as plant-derived fructo-oligosaccharides or dairy-derived galacto-oligosaccharides, which are differentially metabolized and distinct from milk oligosaccharide catabolism. In the following chapter we review bifidobacterial carbohydrate metabolism, as well as several other topics including nitrogen and iron metabolism.

Last Modified: 12/21/2014
Footer Content Back to Top of Page