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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Infectious Bacterial Diseases Research » Research » Publications at this Location » Publication #62429

Title: GENETIC ORGANIZATION IN SPIROCHETES

Author
item Zuerner, Richard

Submitted to: Book Chapter
Publication Type: Book / Chapter
Publication Acceptance Date: 8/28/1996
Publication Date: N/A
Citation: N/A

Interpretive Summary: Spirochetes form a unique branch in bacterial evolution. These bacteria cause diseases in animals and humans. In livestock, the diseases these bacteria cause can result in significant economic loss to the producer. Spirochetes share a common morphology and heritage. Analysis of these bacteria has revealed the existence of unusual and unique features in chromosome structure, composition, and organization. A review of the data on genetic organization of these unusual bacteria is provided.

Technical Abstract: Chromosome structure and organization of the spirochetes is discussed. Comparisons of specific genetic loci among different spirochetal genera is provided. These bacteria exhibit a remarkable diversity of chromosome structure and composition. Variation in genetic organization is seen among highly conserved loci. Stability in genetic organization varies among different genera. Some spirochetal genera have very stable genomes while others are quite variable. Unique and unusual features are also seen in analysis of plasmid DNA in these bacteria.