Technical Abstract: Locoweed is the most widespread poisonous plant problem in the western U.S. Locoweeds are relatively palatable. Many locoweeds are the first plants to start growing in the spring and they may also regrow in the fall. Livestock generally prefer the green-growing locoweeds to other forage that is dormant in the fall, winter, and spring. The most effective management strategy is to deny livestock access to locoweeds during critical periods when they are more palatable than associated forage. Reserving locoweed- free pastures or controlling existing locoweed populations with herbicides can provide "safe" pastures for critical periods. Watching animals closely and removing those that begin eating locoweed can prevent further intoxication and prevent them from influencing others to start. Finally, conditioned food aversion is an effective practice to train animals to avoid eating locoweed, and may be economical where losses are large and persisten.