ARS | Publication request: Mechanism of Host-Agent Interactions in Subclinical Salmonella Infection in Pig Herds

Submitted to: International Symposium on Epidemiology and Control of Salmonella in Pork
Publication Type: Proceedings
Publication Acceptance Date: August 22, 1997
Publication Date: N/A

Technical Abstract: Salmonella species are ubiquitous in nature and many factors affect their survival in the environment. Ingestion of the bacterium by humans typically results in acute gastroenteritis. Contaminated foods are thought to play a significant role in the disease. Swine, cattle, and poultry are known to carry Salmonella. Antimicrobics are contraindicated in treatment of the disease. Abuse and overuse of antimicrobics can result in the emergence of resistant populations of bacteria which cause more serious disease. Control of the problem in the animal population typically occurs through modification of management techniques. However, use of competitive exclusion products, harmless bacteria which out compete Salmonella for sites in the intestine, have shown promise in reducing numbers of Salmonella in animals. Control may also be imparted by use of vaccines. This paper describes the pathogenesis of the disease, the carrier state, use of antimicrobics, and defines intervention strategies including use of competitive exclusion and vaccines.