Submitted to: Journal of Animal Science Supplement
Publication Type: Abstract Only
Publication Acceptance Date: March 17, 2012
Publication Date: June 25, 2012
Citation: Sharon, K.P., Duff, G.C., Harbac, M.M., Paterson, J.A., Carroll, J.A., Dailey, J.W. 2012. Effects of timing on vaccination (day 0 versus day 14 of a receiving period) with a modified-live respiratory viral vaccine on performance, feed intake, and febrile response of beef heifers [abstract]. Journal of Animal Science. 90:149(Suppl. 3). Technical Abstract: The objective of this study was to evaluate the effects of timing of administration of a modified-live respiratory viral vaccine (IBR-PI3-BRSV-BVD) on d 0 or on d 14 of a receiving period on performance, feed intake, and febrile response in beef heifers. Our hypothesis was vaccine timing will alter febrile response and feed intake of feeder cattle. Thirty-six heifers (Angus and Angus crosses; initial BW = 265 ± 20 kg) were ranked by BW and assigned to treatment pens (9 pens total) in a completely randomized design. Treatments (3 pens/treatment with 4 heifers/pen) included no vaccine (CON), vaccination on d 0 (DO), and a delayed vaccination on d 14 (D14) of the receiving period. Heifers were fed in 6 x 12 m pens with GrowSafe feeding systems. Daily intakes were recorded and BW measured on d -1, 0, 14, 27, and 28. Temperature probes were attached to controlled intrauterine drug release devices (CIDR; active compound was removed) and vaginal temperatures were recorded every 5 min for the experiment; vaginal temperatures were then averaged for every h before data analysis. All data were analyzed using pen as the experimental unit. No differences (P > 0.10) among treatments were observed for initial BW, final BW, ADG for d 0 to end, or overall G:F. A treatment x d interaction (P < 0.05) was observed for feed intake. Daily intake was decreased for D14 versus D0 on d 14 (P < 0.01) and 15 (P < 0.10) and decreased (P < 0.05) on d 15 for the average of vaccinated calves versus CON. Eating rate (grams consumed/eating duration) was decreased (P < 0.05) on d 14 for D14 versus D0. A treatment x d interaction (P < 0.01) was observed for vaginal temperature. Vaginal temperature was increased (P < 0.10) on d 1 for D0 versus D14 heifers and increased for D14 versus D0 on d 14 (P < 0.01), 15 (P < 0.05) and 16 (P < 0.05). Our results suggest that time of administration of a modified-live respiratory viral vaccine can alter feed intake and vaginal temperature in feeder heifers.