Submitted to: University of Maryland Experiment Station Report
Publication Type: Experiment Station
Publication Acceptance Date: March 29, 2010
Publication Date: March 29, 2010
Repository URL: http://www.lgu.umd.edu/lgu_v2/pages/
Citation: Lunney, J.K. 2010. BARC 2009 Annual Report for NRSP-8 National Animal Genome Research Program (NAGRP). University of Maryland Experiment Station Report. Available: http://www.lgu.umd.edu/_lgu_v2/pages. Technical Abstract: BARC 2009 has contributed to the National Animal Genome Research Program (NAGRP). The NRSP8 NAGRP’s objectives are 1) Enhance and integrate genetic and physical maps of agriculturally important animals for cross species comparisons and sequence annotation; 2) Facilitate integration of genomic, transcriptional, proteomic and metabolomic approaches toward better understanding of biological mechanisms underlying economically important traits; and 3) Facilitate and implement bioinformatic tools to extract, analyze, store and disseminate information. For Obj.1 BARC has collaborated on updates on the nomenclature for the swine leukocyte antigen (SLA) complex and helped to optimize methods for identifying SLA class I and II alleles. For Obj. 2 BARC has helped to validate the utility of the new Pigoligoarray and use it to assess swine responses to Porcine Reproductive and Respiratory Syndrome (PRRS) infection. BARC has led and expanded the PRRS Host Genomic Consortium (PHGC) studies. BARC has assisted the identification and mapping of differentially expressed genes regulating responses to Salmonella infection. Finally BARC has collaborated on the development of a new multiplex bead assay for swine cytokines. For Obj.3 BARC has worked to develop and assure secure data collection for the PHGC by its comprehensive PHGC database.