|Babu, Uma - FDA|
|Raybourne, Richard - FDA|
|Heckert, Robert - VA-MD REG COL. VET MED|
Submitted to: American Veterinary Medical Association Abstract
Publication Type: Abstract Only
Publication Acceptance Date: May 1, 2002
Publication Date: May 1, 2003
Citation: OKARMURA, M., LILLEHOJ, H.S., BABU, U.S., RAYBOURNE, R.B., HECKERT, R.A. CELLULAR IMMUNE RESPONSES VACCINATED WITH SALMONELLA ENTERITIDIS BACTERIN. AMERICAN VETERINARY MEDICAL ASSOCIATION ABSTRACT. 2003. Technical Abstract: The effects of Salmonella enteritidis vaccination on the host cellular immune response was evaluated. Chickens were vaccinated subcutaneously with killed S. enteritidis vaccine at the ages of 3 and 5 weeks. After vaccination, serum samples were collected for 3 weeks for the evaluation of IFN- and IL-2 levels. The IFN- level was significantly (p<0.05) higher in the vaccine group at 7, 11, 14, and 21 days post vaccination (dpv) whereas the IL-2 level was higher at 14, 18, and 21 dpv. Therefore, killed S. enteritidis vaccine induce important chicken cytokines which are involved in the elimination of the intracellular Salmonella.