Submitted to: American Chemical Society Abstracts
Publication Type: Abstract Only
Publication Acceptance Date: August 22, 2002
Publication Date: August 22, 2002
Citation: Saha, B.C. 2002. Production of mannitol by fermentation [abstract]. American Chemical Society. Paper No. BIOT 0121. Technical Abstract: Mannitol, a naturally occurring polyol, is widely used in the food, pharmaceutical, medicine and chemical industry. The production of mannitol by fermentation has become attractive because of the problems associated with its production by chemical methods. We have selected Lactobacillus intermedius NRRL B-3693 as a good producer of mannitol after screening 72 bacterial cultures from the ARS Culture Collection. In this presentation, our research dealing with the factors affecting the production of mannitol by the bacterium in pH-controlled batch and fed-batch fermentations will be described. Recent progress on the production of mannitol by fermentation and using enzyme technology will be reviewed. The problems and prospects of mannitol production by fermentation and enzymatic means and future directions of research will be highlighted.