Project Number: 1235-51530-053-09
Project Type: Specific Cooperative Agreement

Start Date: Sep 18, 2011
End Date: Sep 17, 2016

Objective:
The objective of this agreement is to work together to conduct studies examining the effects of phytochemicals on cancer cells and cancer stem cells. Studies will focus on genes important in the process of carcinogenesis.

Approach:
ARS will use cell culture models of prostate cancer cells or prostate cancer stem cells to test the effects of diet-derived phytochemicals on their ability to inhibit carcinogenesis. The focus will be on cellular pathways that may be important in the carcinogenesis process, including steroid hormone-related pathways, xenobiotic metaboism, etc.