Page Banner

United States Department of Agriculture

Agricultural Research Service

Related Topics

Research Project: Development of a Prebiotic Intervention to Reduce Carriage of Zoonotic Pathogens of Swine During on-Farm Rearing and Entering the Abattoir

Location: Food and Feed Safety Research

Project Number: 6202-32000-030-66
Project Type: Trust

Start Date: May 01, 2014
End Date: Oct 30, 2015

Objective:
1) Determine the inhibitory concentration of thymol-beta-D-glucopyranoside (called beta-D-thymol) needed to achieve efficacious reductions of Campylobacter coli, Salmonella spp., and E. coli in laboratory and animal feeding studies. 2) Evaluate the potential of beta-D-thymol to co-select for antibiotic-resistant Campylobacter coli, Salmonella spp., and generic E. coli or to make resistant strains of these bacteria more sensitive to antibiotics when grown in mixed populations of porcine gut bacteria.

Approach:
A series of laboratory and live animal studies will be conducted to test the effects of a novel antimicrobial compound, thymol-beta-D-glucopyranoside, on the survivability and antimicrobial susceptibility of zoonotic pathogens.

Last Modified: 9/10/2014
Footer Content Back to Top of Page