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United States Department of Agriculture

Agricultural Research Service

Related Topics

Research Project: Antioxidant Polyphenols in Impaired Brain and Heart Functions Associated with Obesity and Metabolic Diseases

Location: Diet, Genomics and Immunology Lab

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)

Flaxseed lignan and visceral obesity: a closer look at its chemical properties, absorption, metabolism, bioavailability and effects on visceral fat, lipid profile, systemic inflammation and hypertension - (Book / Chapter)
Park, J.B. 2014. Flaxseed lignan and visceral obesity: a closer look at its chemical properties, absorption, metabolism, bioavailability and effects on visceral fat, lipid profile, systemic inflammation and hypertension. In: Watson, R.R., Academic Press. Nutrition in the Prevention and Treatment of Abdominal Obesity. 1st edition. San Diego, CA: Academic Press. p317-328.
Cinnamon counteracts the negative effects of a high fat/high fructose diet on behavior, brain insulin signaling and Alzheimer-associated changes - (Peer Reviewed Journal)
Anderson, R.A., Qin, B., Canini, F., Poulet, L., Roussel, A.M. 2013. Cinnamon counteracts the negative effects of a high fat/high fructose diet on behavior, brain insulin signaling and Alzheimer-associated changes. PLoS One. 8(12):e83243.
Cinnamon polyphenols regulate S100ß, sirtuins, and neuroactive proteins in rat C6 glioma cells - (Peer Reviewed Journal)
Qin, B., Panickar, K., Anderson, R.A. 2013. Cinnamon polyphenols regulate S100ß, sirtuins, and neuroactive proteins in rat C6 glioma cells. Journal of Nutrition. 30(2):210-217.
Effects of secoisolariciresinol diglucoside lignan-enriched flaxseed powder on body weight, visceral fat, lipid profile, adipokines, and blood pressure in rats fed a high-fructose and high-fat diet - (Peer Reviewed Journal)
Park, J.B., Velasquez, M.T. 2012. Effects of secoisolariciresinol diglucoside lignan-enriched flaxseed powder on body weight, visceral fat, lipid profile, adipokines, and blood pressure in rats fed a high-fructose and high-fat diet. Fitoterapia. 83(5):941-6.
Mechanisms responsible for hepatic very low density lipoprotein-apoB100 overproduction in Otsuka Long-Evans Tokushima fatty rats - (Peer Reviewed Journal)
Qin, B., Anderson, R.A., Kuzuya, T., Kitaura, Y., Shinomura, Y. 2012. Mechanisms responsible for hepatic very low density lipoprotein-apoB100 overproduction in Otsuka Long-Evans Tokushima fatty rats. Atherosclerosis. 222:407-416.
Cinnamon polyphenols regulate multiple metabolic pathways involved in intestinal lipid metabolism of primary small intestinal enterocytes - (Peer Reviewed Journal)
Qin, B., Dawson, H.D., Schoene, N.W., Polansky, M.M., Anderson, R.A. 2012. Cinnamon polyphenols regulate multiple metabolic pathways involved in intestinal lipid metabolism of primary small intestinal enterocytes. European Journal of Nutrition. 28:1172-79.
Safflomide increases the expression of adiponectin in vitro and in vivo: Implication for hypoadiponectemia, visceral obesity, and insulin resistance - (Peer Reviewed Journal)
Park, J.B., Wang, T.T. 2012. Safflomide increases the expression of adiponectin in vitro and in vivo: Implication for hypoadiponectemia, visceral obesity, and insulin resistance. Journal of Agricultural and Food Chemistry. 25(60):4048-52.
A procyanidin type A trimer from cinnamon extract attenuates glial cell swelling and the reduction in glutamate uptake following ischemic injury in vitro - (Peer Reviewed Journal)
Panickar, K.S., Polansky, M.M., Graves, D.J., Urban Jr, J.F., Anderson, R.A. 2012. A procyanidin type A trimer from cinnamon extract attenuates glial cell swelling and the reduction in glutamate uptake following ischemic injury in vitro. Neuroscience. 202:87-98.
Effect of polyphenols on oxidative stress and mitochondrial dysfunction in neuronal death, brain edema, and cell swelling in cerebral ischemia - (Review Article)
Panickar, K.S., Anderson, R.A. 2011. Effect of polyphenols on oxidative stress and mitochondrial dysfunction in neuronal death, brain edema, and cell swelling in cerebral ischemia. International Journal of Molecular Sciences. 12:8181-8207.
An extract of chokeberry attenuates weight gain and modulates multiple signaling pathways in epididymal adipose tissue of rats fed a fructose-rich diet - (Peer Reviewed Journal)
Anderson, R.A., Qin, B. 2011. An extract of chokeberry attenuates weight gain and modulates multiple signaling pathways in epididymal adipose tissue of rats fed a fructose-rich diet. British Journal of Nutrition. 108:581-587.
Mechanisms underlying the protective effects of myricetin and quercetin following oxygen/glucose deprivation-induced cell swelling and the reduction in glutamate uptake in glial cells - (Peer Reviewed Journal)
Panickar, K.S., Anderson, R.A. 2011. Mechanisms underlying the protective effects of myricetin and quercetin following oxygen/glucose deprivation-induced cell swelling and the reduction in glutamate uptake in glial cells. Journal of Neuroscience. 183:1-14.
Cinnamon increases liver glycogen in an animal model of insulin resistance - (Peer Reviewed Journal)
Couturier, K., Qin, B., Batandier, C., Awada, M., Hininger, I., Canini, F., Leverve, X., Roussel, A., Anderson, R.A. 2011. Cinnamon increases liver glycogen in an animal model of insulin resistance. Metabolism. 60(11):1590-7.
Identification and quantification of a major anti-oxidant and anti-inflammatory phenolic compound found in basil, lemon, thyme, mint, oregano, rosemary, sage, and thyme - (Peer Reviewed Journal)
Park, J.B. 2011. Identification and quantification of a major anti-oxidant and anti-inflammatory phenolic compound found in basil, lemon, thyme, mint, oregano, rosemary, sage, and thyme. International Journal of Food Sciences and Nutrition. 62(6):577-584.
Protective effects of veskamide, enferamide, becatamide, and oretamide on H2O2-induced apoptosis of PC-12 cells - (Peer Reviewed Journal)
Park, J.B. 2011. Protective effects of veskamide, enferamide, becatamide, and oretamide on H2O2-induced apoptosis of PC-12 cells. Phytomedicine. 18(10):843-847.
Cinnamon polyphenol extract regulates tristetraprolin and related gene expression in mouse adipocytes - (Peer Reviewed Journal)
Cao, H., Anderson, R.A. 2011. Cinnamon polyphenol extract regulates tristetraprolin and related gene expression in mouse adipocytes. Journal of Agricultural Food & Chemistry. 59(6):2739-2744.
Dietary polyphenols exert neuroprotective effects by attenuating neuronal and astrocytic damage in cerebral ischemia - (Book / Chapter)
Panickar, K.S., Anderson, R.A. 2011. Dietary polyphenols exert neuroprotective effects by attenuating neuronal and astrocytic damage in cerebral ischemia. In: Farooqui, A.A., Farooqui, T., 1st Edition. New York, NY: Nova. p135-155.
Chromium - (Review Article)
Anderson, R.A., Cefalu, W.T. 2011. Chromium. In: Coates, P.M., Betz, J.M., Blackman, M.R., Cragg, G.M., Levine, M., Moss, J., and White, J.D., editors. Encyclopedia of Dietary Supplements, 2nd Edition, New York, N.Y.: Marcel Dekker, p. 148-156.
Cinnamon improves insulin sensitivity and alters body composition in an animal model of the metabolic syndrome - (Peer Reviewed Journal)
Couturier, K., Batandier, C., Awada, M., Hininger, I., Canini, F., Anderson, R.A., Leverve, X., Roussel, A. 2010. Cinnamon improves insulin sensitivity and alters body composition in an animal model of the metabolic syndrome. Archives Of Biochemistry and Biophysics. 501(1):158-61.
Cinnamon: potential role in the prevention of insulin resistance, metabolic syndrome, and type 2 diabetes - (Peer Reviewed Journal)
Qin, B., Panickar, K.S., Anderson, R.A. 2010. Cinnamon: potential role in the prevention of insulin resistance, metabolic syndrome, and type 2 diabetes. Journal of Diabetes Science and Technology. 4(3):685-693.
Selenium compounds activate early barriers of tumorigenesis - (Peer Reviewed Journal)
Wu, M., Kang, M., Schoene, N.W., Cheng, W. 2010. Selenium compounds activate early barriers of tumorigenesis. Journal of Biological Chemistry. 285(16):12055-12062.
Novel angiogenesis inhibitory activity in cinnamon extract blocks VEGFR2 kinase and downstream signaling - (Peer Reviewed Journal)
Lu, J., Zhang, K., Nam, S., Anderson, R.A., Jove, R., Wen, W. 2010. Novel angiogenesis inhibitory activity in cinnamon extract blocks VEGFR2 kinase and downstream signaling. Carcinogenesis. 31:481-488.
Chromium III histidinate exposure modulates antioxidant gene expression in HaCaT human keratinocytes exposed to oxidative stress - (Peer Reviewed Journal)
Puch, F., Benaraba, R., Hazane, F., Valenti, K., Osman, M., Laporte, F., Favier, A., Anderson, R.A., Roussel, A., Hininger, I. 2010. Chromium III histidinate exposure modulates antioxidant gene expression in HaCaT human keratinocytes exposed to oxidative stress. Biological Trace Element Research. (137):23-39.
Cinnamon extract regulates plasma levels of adipose-derived factors and expression of multiple genes related to carbohydrate metabolism and lipogenesis in adipose tissue of fructose-fed rats - (Peer Reviewed Journal)
Qin, B., Polansky, M.M., Anderson, R.A. 2010. Cinnamon extract regulates plasma levels of adipose-derived factors and expression of multiple genes related to carbohydrate metabolism and lipogenesis in adipose tissue of fructose-fed rats. Hormone and Metabolic Research. 42:187-193.
Role of dietary polyphenols in attenuating brain edema and cell swelling in cerebral ischemia - (Review Article)
Panickar, K.S., Anderson, R.A. 2010. Role of dietary polyphenols in attenuating brain edema and cell swelling in cerebral ischemia. Recent Patents on Central Nervous System Drug Discovery. 5(2):99-108.
Cinnamon improves insulin sensitivity, prevents mesenteric fat accumulation, and increases glycogen synthesis in an animal model of the metabolic syndrome - (Abstract Only)
Couturier, K., Batandier, C., Awada, M., Hininger, I., Osman, M., Poulet, L., Canini, F., Mormede, P., Anderson, R.A., Roussel, A. 2009. Cinnamon improves insulin sensitivity, prevents mesenteric fat accumulation, and increases glycogen synthesis in an animal model of the metabolic syndrome. Meeting Abstract.
Characterization of the metabolic and physiologic response to chromium supplementation in subjects with type 2 diabetes mellitus - (Peer Reviewed Journal)
Cafalu, W.T., Rood, J., Pinsonat, P., Qin, J., Sereda, O., Levitan, L., Anderson, R.A., Zhang, X.H., Martin, J.M., Martin, C.K., Wang, Z.Q., Newcomer, B. 2010. Characterization of the metabolic and physiologic response to chromium supplementation in subjects with type 2 diabetes mellitus. Metabolism. 59(3):755-762.
Green tea polyphenols improve cardiac muscle mRNA, and protein levels of signal pathways related to insulin and lipid metabolism and inflammation in insulin-resistant rats - (Peer Reviewed Journal)
Qin, B., Polansky, M.M., Dawson, H.D., Anderson, R.A. 2010. Green tea polyphenols improve cardiac muscle mRNA, and protein levels of signal pathways related to insulin and lipid metabolism and inflammation in insulin-resistant rats. Molecular Nutrition and Food Research. 54(S1)S14-S23.
Influence of zinc deficiency on AKT-MDM2-P53 signaling axes in normal and malignant human prostate cells - (Peer Reviewed Journal)
Han, C.T., Schoene, N.W., Lei, K.Y. 2009. The influence of zinc deficiency on AKT-MDm2-p53 signaling axes in normal and malignant human prostate cells. American Journal of Physiology - Cell Physiology. 297(5):C1188-1199.
Myricetin and quercetin attenuate ischemic injury in glial cultures by different mechanisms - (Proceedings)
Panickar, K.S., Polansky, M.M., Anderson, R.A. 2009. Myricetin and quercetin attenuate ischemic injury in glial cultures by different mechanisms. Society for Neuroscience Abstracts and Proceedings.
Cinnamon extract inhibits tau aggregation associated with Alzheimer’s Disease in vitro - (Peer Reviewed Journal)
Peterson, D.W., George, R.C., Scaramozzino, F., Lapointe, N.E., Anderson, R.A., Graves, D.J., Lew, J. 2009. Cinnamon extract inhibits tau aggregation associated with Alzheimer’s Disease in vitro. Journal of Alzheimer's Disease. 17(3):585-597.
Cinnamon extract attenuates TNF-alpha-induced intestinal lipoprotein ApoB48 overproduction by regulating inflammatory, insulin, and lipoprotein pathways in enterocytes - (Peer Reviewed Journal)
Qin, B., Dawson, H.D., Polansky, M.M., Anderson, R.A. 2009. Cinnamon extract attenuates TNF-alpha-induced Intestinal lipoprotein ApoB48 overproduction by regulating inflammatory, insulin and lipoprotein pathways in enterocytes. Hormone and Metabolic Research. 41:1-7.
Cinnamon extract regulates intestinal lipid metabolism related gene expression in primary enterocytes of rats - (Abstract Only)
Qin, B., Polansky, M.M., Anderson, R.A. 2009. Cinnamon extract regulates intestinal lipid metabolism related gene expression in primary enterocytes of rats. BARC Poster Day.
Last Modified: 8/27/2014
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