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ARS Home » Research » Publications at this Location » Publication #60005
Title: PATHOLOGY OF EXPERIMENTAL ASPERGILLOSIS IN TURKEYS

Author
item Kunkle, Robert
item Rimler, Richard - Rick

Submitted to: American Veterinary Medical Association Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 5/1/1995
Publication Date: N/A
Citation: N/A

Interpretive Summary:

Technical Abstract: The pathologic changes in the lower respiratory tract of turkeys were characterized by light microscopy after intra-airsac inoculation of Aspergillus fumigatus. The character and severity of airsacculitis were similar at 24 through 96 hours post-inoculation (PI). Lesions included severe lymphohistiocytic perivasculitis and multifocal granulomas containing multinucleate giant cells. Lung lesions progressed from mild interstitial pneumonia to extensive effacement by multifocal coalescing granulomas, necrosis, and hemorrhage. Severe pleuritis with local extension into lung parenchyma was seen at all timepoints. Numbers of intralesional fungal elements decreased in airsac membranes and increased in lung tissues from 24 to 96 hours PI.