Author
Register, Karen | |
IVANOV, YURY - Pennsylvania State University | |
HARVILL, ERIC - Pennsylvania State University | |
BRINKAC, LAUREN - J Craig Venter Institute | |
KIM, MARIA - J Craig Venter Institute | |
LOSADA, LILIANA - J Craig Venter Institute |
Submitted to: Genome Announcements
Publication Type: Peer Reviewed Journal Publication Acceptance Date: 2/10/2015 Publication Date: 3/25/2015 Publication URL: http://handle.nal.usda.gov/10113/61255 Citation: Register, K.B., Ivanov, Y.V., Harvill, E.T., Brinkac, L., Kim, M., Losada, L. 2015. Draft genome sequences of six Bordetella hinzii isolates acquired from Avian and Mammalian hosts. Genome Announcements. 3(20). e00081-15. DOI: 10.1128/genomeA.00081-15. Interpretive Summary: Bordetella hinzii is a bacterium that is known to infect poultry, humans, rabbits and rodents. It can cause serious disease in humans whose immune system has been compromised and some strains cause mild to moderate respiratory disease in turkeys. Little is known about the degree of variation that exists among different strains or about the genetic basis for virulence. Here, we report the genome sequences of six isolates of B. hinzii collectively acquired from humans, rabbits and turkeys. These data provide a framework for refining the population structure of the bacterium and other Bordetella species, establishing relationships among genetically distinct isolates and developing an understanding of possible virulence mechanisms of B. hinzii. Technical Abstract: Bordetella hinzii is a Gram-negative bacterium known to infect poultry, humans, rabbits and rodents. It is an opportunistic pathogen in immunocompromised humans and some strains cause mild to moderate respiratory disease in turkeys. Little is known as to the degree of genetic diversity within the species or the genetic basis for virulence. Here, we report the genome sequences of six isolates of B. hinzii collectively acquired from humans, rabbits and turkeys. These data provide a framework for refining the population structure of the genus, establishing relationships among genetically distinct isolates and developing an understanding of possible virulence mechanisms of the bacterium. |