Author
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Nachman, Ronald |
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Submitted to: Peptides
Publication Type: Peer Reviewed Journal Publication Acceptance Date: 11/18/2010 Publication Date: 3/1/2011 Citation: Nachman, R.J. 2011. Introduction: Invertebrate Neuropeptides XI. Peptides. 32(3):433. Interpretive Summary: This publication represents an introduction to the eleventh in a series of special issues of the Peptides journal dedicated to invertebrate neuropeptides, short chains of amino acids that serve as potent messengers to regulate vital functions. The issue addresses a number of aspects of invertebrate neuropeptide research including identification of novel characterization of new biological roles for existing neuropeptides, elucidation of the mechanisms and biochemical pathways through which neuropeptides operate, and aspects of neuropeptide metabolism. In addition, several papers address the design and evaluation of neuropeptide mimics that resist metabolism and enhance the ability to overstimulate and disrupt neuropeptide-regulated function, and their significance to the development of novel, neuropeptide-based strategies for management of arthropod pests. Technical Abstract: This publication represents an introduction to the eleventh in a series of special issues of the Peptides journal dedicated to invertebrate neuropeptides. The issue addresses a number of aspects of invertebrate neuropeptide research including identification of novel characterization of new biological roles for existing neuropeptides, elucidation of the mechanisms and biochemical pathways through which neuropeptides operate, and aspects of neuropeptide metabolism. In addition, several papers address the design and evaluation of metabolically-resistant mimetic analogs with enhanced ability to overstimulate and disrupt neuropeptide-regulated function, and their significance to the development of novel, neuropeptide-based strategies for management of arthropod pests. |
