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United States Department of Agriculture

Agricultural Research Service

Research Project: Linking Foods, Behavior and Metabolism to Promote a Healthy Body Weight

Location: Obesity and Metabolism Research Unit

Title: Neuromedin and FN-38 Peptides for Treating Psychiatric Diseases

Authors
item Laugero, Kevin
item Hanley, Michael -
item Parkes, David -
item Mcgonicle, Paul -

Submitted to: U.S. Patent and Trademark Office
Publication Type: Other
Publication Acceptance Date: February 4, 2008
Publication Date: July 1, 2010
Citation: Laugero, K.D., Hanley, M.R., Parkes, D.G., Mcgonicle, P. 2010. Neuromedin and FN-38 Peptides for Treating Psychiatric Diseases. Patent Application.

Interpretive Summary: This publication further supports an important relationship between the gut-brain axis, central stress pathways, and psychiatric health, and reports concepts and experimental results supporting the use of metabolic neuromedin peptides for treating neurobehavioral and stress-related diseases and conditions, including schizophrenia; depression, and anxiety.

Technical Abstract: Methods and compositions for treating psychiatric diseases and disorders are disclosed. The methods provided generally involve the administration of an NMX peptide, an FNX peptide, or an NMX receptor agonist, or analogs or derivatives thereof, to a subject in order to treat psychiatric diseases and disorders, and conditions associated with psychiatric diseases and disorders.

Last Modified: 4/18/2014
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