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Submitted to: Journal of the Japanese Association of Mycotoxicology
Publication Type: Review Article Publication Acceptance Date: 2/24/2004 Publication Date: 5/20/2004 Citation: Maragos, C.M. 2004. Recent advances in analytical methods for mycotoxins. In: Yoshizawa, T., editor. New Horizon of Mycotoxicology for Assuring Food Safety. Japanese Association of Mycotoxicology, November 3-5, 2003, Takamatsu, Japan. p. 215-223. Interpretive Summary: Technical Abstract: Accurate and sensitive methods for detection of the major mycotoxins have been developed and improved for many years. Immunoassays, first introduced for mycotoxins in the 1970's, have found widespread use as screening tools. Despite the success of the enzyme-linked immunoassay (ELISA) format, new formats for immunoassays continue to be explored with the goal of improving upon the speed and ease-of-use of the assays. Recent advances in analytical technologies have allowed the adaptation of immunoassays to a wide variety of new formats. This review focuses on the recent developments in detection technologies for mycotoxins, in particular those using antibodies as the recognition element (immunosensors). Recent developments in surface plasmon resonance, fiber optic sensors, membrane-based immunoassays, fluorescence-based assays, and capillary-based immunoassays, are presented. The challenge remaining for many of these new technologies is one of making the transition from laboratory-based assays to validated field-portable screening assays. |
