Submitted to: Research Workers in Animal Diseases Conference Proceedings
Publication Type: Abstract Only
Publication Acceptance Date: 11/8/1998
Publication Date: N/A
Citation: Interpretive Summary:
Technical Abstract: Neonatal calves are susceptible to disease, especially after known acute stressors such as transport. A good indicator of animal susceptibility or resistance during the period following acute stress has not been found. We investigated the effect of electrolyte administration on well-being of neonatal calves following transport stress. Fifteen calves were assigned to one of three treatments; control (non-transported calves), transported, or transported with electrolytes. Calves were sampled by jugular venipuncture prior to a four hour transport and overnight penning with same age calves. The following day, calves were transported for four more hours. Calves in the electrolyte treatment then received 1 liter of electrolyte subcutaneously. Calves were sampled on d 4, 8, 11, 15, and 18 of the study. Samples were used for lymphocyte phenotyping: CD4, CD8, gamma delta (TcR1), and WC-1. Two acute phase proteins, haptoglobin and alpha lacid-glycoprotein, and plasma IgG were determined from the plasma. Acute phase proteins did not reflect any transport induced charges. Lymphocyte phenotyping revealed an increase in CD4 at d 4 and a trend for increased CD4 at d 18. CD4:CD8 ratio reflected the pattern of the CD4 positive cells on d 4, with an increase associated with electrolyte administration following transport. Gamma delta T-cell marker increased non-significantly at d 11 and 18 and WC1 did not change with transport. IgG concentrations increased in calves receiving electrolytes at d 18 compared to the other two treatments. These data indicate that electrolyte solution administration to stressed calves may be beneficial by altering lymphocyte populations and antibody concentrations, besides the rehydration benefit.