Submitted to: Zeitschrift Fur Naturforschung
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 10/6/1998
Publication Date: N/A
Interpretive Summary: Proteins with slippery properties (lipopeptides) are produced by many bacteria, which enables them to grow on surfaces that do not absorb water, such as plant leaf or stem surfaces. Bacteria have also evolved ways to make iron-binding compounds (siderophores), which allow them to grow under conditions where very little iron is available. The second example of a rarely found compound, a lipopeptide siderophore, has been discovered by German scientists in collaboration with the US Department of Agriculture (USDA). The group isolated the compound from a bacterium (Pseudomonas corrugata) that causes tomato stems to rot. They next determined the chemical structure of the compound and named it corrugatin. Bacteria in the Pseudomonas class (genus) are important because they cause many plant diseases that are responsible for millions of dollars in crop losses. The results of their cooperative work will be valuable for resolving the taxonomical placement of the tomato pathogen Pseudomonas corrugata within the Pseudomonas genus. This will allow more accurate identification of bacterial plant pathogens, a necessary prerequisite for targeting their control and the control of the diseases they cause.
Technical Abstract: From the culture medium of the phytopathogenic bacterium Pseudomonas corrugata, a lipopeptide siderophore was isolated that comprises interesting structural elements such as cyclic condensation products of the two amino groups of 2,4-diamino butyric acid with the carboxyl group of a second amino acid, and the rarely encountered L-threo-B-hydroxy histidine.