Submitted to: American Journal of Veterinary Research
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 3/31/1998
Publication Date: N/A
Interpretive Summary: Respiratory tract disease is a leading cause of economic loss to the cattle industry. Adenoviruses are known to produce both respiratory and enteric disease in cattle. The bovine adenoviruses (BAdVs) have been isolated from healthy cattle but more frequently the isolations are associated with some form of clinical disease. Little is known about the distribution of BAdVs in the cattle population in the United States. Serologic studies can clarify the epidemiological significance of the BAdVs. The purpose of the present study was to determine BAdV prevalence and the seroconversion rate in paired sera from 100 calves. Serum antibodies were found to all the of BAdV used in the study and seroconversion had occurred in some of the calves indicating that the adenoviruses were present and producing active infections in these calves. The serologic data provides the first evidence for the presence of some of the BAdV serotypes in the United States cattle population.
Technical Abstract: Adenovirus serum antibody was measured by a microtitration test to determine the prevalence of antibody to bovine adenovirus serotype 1 (BAdV- 1) through BAdV-8 and BAdV-10 at the farm and again after 5 weeks in a feedyard. Although only BAdV-1 through -4, -7, and -10 have been isolated from cattle in the United States, serum antibodies were found to the nine serotypes of bovine adenovirus used in the study. Seroconversion had occurred in some of the calves for each virus by the time the second serum sample had been collected indicating that the adenoviruses were present and producing active infections in these calves.