|Nisbet, David - Dave|
|Byrd, James - Allen|
Submitted to: United States Animal Health Association Proceedings
Publication Type: Proceedings
Publication Acceptance Date: 4/27/1996
Publication Date: N/A
Citation: N/A Interpretive Summary:
Technical Abstract: Previously defined competitive exclusion cultures developed in our laboratory have increased the resistance to salmonellae colonization in chickens when provided to them on the day they are hatched. Using similar methods, a culture has been developed for pigs. The litters from three sows were assigned to 3 different experimental groups, non Salmonella challenged negative controls (group 1), Salmonella challenged positive controls(group 2), and a Salmonella challenged culture treated litter (group 3). The litter receiving the culture were provided 5 mls of culture at 4 hr and 24 hr post farrowing. Pigs in group 2 and 3 were challenged with 1,000 tetracyline resistant S. cholerasuis. Pigs were sacrificed 7 days after challenge and Salmonella gut colonization measured. Because both control groups of pigs were shedding serotype B Salmonella, no data for the S. cholerasuis is given and colonization control data is based upon total salmonellae cultivated. Pigs fecal samples were collected by rectal swab as an indicator of salmonellae shedding from farrow until the termination of the experiment. Salmonella positive rectal swabs were 85%, 100%, and 18%, respectively, for unchallenged controls (GP 1), challenged controls (GP 2), and CF-treated litter (GP 3). Salmonellae positive colonic samples were 100%, 67% and 0% for groups 1, 2 and 3, respectively. Ileal cecal junction salmonellae positive samples were 80%, 100%, and 14% for groups 1, 2, and 3, respectively. Cecum salmonellae positive samples for groups 1, 2, and 3 were 80%, 100%, and 0%, and salmonellae cecal positive samples for these groups were 80%, 100%, and 28%, respectively. Total salmonellae cfu in cecal and ileal cecal contents were also decreased in the CF treated group compared to control groups.