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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Infectious Bacterial Diseases Research » Research » Publications at this Location » Publication #59132


item Whipple, Diana

Submitted to: Livestock Conservation Institute Proceedings
Publication Type: Proceedings
Publication Acceptance Date: 4/7/1995
Publication Date: N/A
Citation: N/A

Interpretive Summary:

Technical Abstract: Programs for control and eradication of bovine tuberculosis in the United States were initiated in 1917. These programs reduced the prevalence of bovine tuberculosis from 5% in 1918 to less than 0.02% in 1994. Although the disease has nearly been eradicated from the United States, finishing this task, with current fiscal constraints, will require better use of existing diagnostic tests and development of improved tests. Research is needed to develop a better understanding of the pathogenesis of tuberculosis in animals so that improved tests and control strategies can be developed. Bovine tuberculosis research programs have been initiated by several universities and agencies of USDA. Research efforts are directed toward accomplishing the following generalized objectives: 1) Evaluate tests for diagnosis of tuberculosis in cattle, deer, elk, and llama; 2) Develop improved diagnostic tests; 3) Determine molecular mechanisms of Mycobacterium bovis infection; 4) Develop methods for differentiation of M bovis strains; and 5) Develop vaccines to protect against tuberculosis.