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ARS Home » Research » Publications at this Location » Publication #58844
Title: THE IMPORTANCE OF ANTIGENIC VARIATION IN VACCINE DESIGN (1994)

Author
item BROWN, FRED - YALE UNIVERSITY

Submitted to: Archives of Virology
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 1/1/1994
Publication Date: N/A
Citation: N/A

Interpretive Summary: One of the more important problems in foot-and-mouth disease is the occurrence of the virus as several variants which differ so much that infection or vaccination with one variant does not confer protection against other variants. This problems is particularly important in the selection of viruses to be made into vaccines.

Technical Abstract: The theme of this lecture was to emphasis the importance of antigenic variation in the preparation of vaccines against foot-and-mouth disease. It drew on several incidents in the field and recent laboratory experiments with a virus of serotype A.