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Research Project: Prevention of Obesity Related Metabolic Diseases by Bioactive Components of Food Processing Waste Byproducts and Mitigation of Food Allergies

Location: Healthy Processed Foods Research

Title: New allergens approved by the WHO/IUIS Allergen Nomenclature Sub-Committee in 2021-2024 and their significance for future diagnostics, regulation, and research. An EAACI Task Force report

Author
item RADAUER, CHRISTIAN - Medical University Of Veinna
item GADERMAIER, GABRIELE - Paracelsus Medical Private University
item GOODMAN, RICHARD - University Of Nebraska
item JACQUET, ALAIN - Chulalongkorn University
item JAPPE, UTA - University Of Lubeck
item LOPATA, ANDREAS - James Cook University
item POMÉS, ANNA - Inbio
item RAULF, MONIKA - World Health Organization (WHO)
item SANTOS, KEITY - Universidad De Sao Paulo
item ZAKZUK, JOSEFINA - University Of Cartagena
item Zhang, Yuzhu
item VITTE, JOANA - Universite De Reims Champagne-Ardenne

Submitted to: Allergy
Publication Type: Review Article
Publication Acceptance Date: 11/11/2025
Publication Date: 11/29/2025
Citation: Radauer, C., Gadermaier, G., Goodman, R., Jacquet, A., Jappe, U., Lopata, A., Pomés, A., Raulf, M., Santos, K., Zakzuk, J., Zhang, Y., Vitte, J. 2025. New allergens approved by the WHO/IUIS Allergen Nomenclature Sub-Committee in 2021-2024 and their significance for future diagnostics, regulation, and research. An EAACI Task Force report. Allergy. 81(3):648-699. https://doi.org/10.1111/all.70166.
DOI: https://doi.org/10.1111/all.70166

Interpretive Summary:

Technical Abstract: The WHO/IUIS Allergen Nomenclature Sub-Committee is an international body of experts that maintains and develops the systematic nomenclature of allergenic proteins. Researchers who identify new allergens are asked to obtain an official allergen name from the sub-committee before publishing their data. Here, we summarize the data on new allergens approved in the years 2021-2024. During this period, the sub-committee assigned names to 111 new allergens with 123 isoallergens/variants as well as 26 new isoallergens/variants of previously known allergens. Most new allergens were respiratory allergens from animals (35 allergens) and plants (25) as well as food allergens from animals (21) and plants (17). Many newly identified allergens reflect globalized allergen exposure and growing research activities outside of Western countries. This is illustrated by allergens from the tropical mite Blomia tropicalis, pollen allergens from tree and weed species native to Asia, and food allergens from regionally important foods such as mango, seafood, silkworm pupae, and natto. The allergen profiles of most relevant sources are well established, but gaps in our knowledge remain, particularly regarding allergens important for populations outside of Europe and North America. The growing number of known allergens highlights the importance of a consistent, unambiguous allergen nomenclature