Skip to main content
ARS Home » Northeast Area » Beltsville, Maryland (BARC) » Beltsville Agricultural Research Center » Animal Parasitic Diseases Laboratory » Research » Publications at this Location » Publication #427615
Research Project: Immune and Genomic Determinants of Host Responses Associated with Porcine Reproductive and Respiratory Syndrome Virus Infections

Location: Animal Parasitic Diseases Laboratory

Title: Progress and challenges in developing swine immune reagents

Author
item Lunney, Joan

Submitted to: Veterinary Immunology and Immunopathology
Publication Type: Review Article
Publication Acceptance Date: 7/7/2025
Publication Date: 7/10/2025
Citation: Lunney, J.K. 2025. Progress and challenges in developing swine immune reagents. Veterinary Immunology and Immunopathology. 286. Article e110975. https://doi.org/10.1016/j.vetimm.2025.110975.
DOI: https://doi.org/10.1016/j.vetimm.2025.110975

Interpretive Summary:

Technical Abstract: Swine immune reagents are required for scientists to reveal the mechanisms underlying responses to infectious disease and vaccines. This review highlights availability of antibodies and immune proteins to assess complex cellular and tissue interactions and the issues involved in assuring the best panel of reagents continue to be available for the research community. Continuing issues are discussed for the production, characterization and availability of expressed swine immune proteins and monoclonal antibodies (mAbs) reactive with those proteins and immune cell subset CD (cluster of differentiation) markers. Finally, suggestions are presented for future investments in veterinary immune toolkit efforts.