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ARS Home » Midwest Area » Columbia, Missouri » Plant Genetics Research » Research » Publications at this Location » Publication #420134

Research Project: Validate Causative Mutations in Agriculturally-Important Vertebrates

Location: Plant Genetics Research

Title: Cryopreservation of biological materials: applications and economic perspectives

Author
item Aarattuthodi, Suja
item Kang, David
item GUPTA, SANJAY - Icar – Indian Institute Of Agricultural Biotechnology (IIAB)
item Chen, Paula
item Redel, Bethany
item MATUHA, MOUREEN - Lincoln University Of Missouri
item MOHAMMED, HAITHAM - Texas A&M University
item SINHA, AMIT KUMAR - University Of Arkansas At Pine Bluff

Submitted to: In Vitro Cellular and Developmental Biology - Animal
Publication Type: Review Article
Publication Acceptance Date: 2/9/2025
Publication Date: 4/23/2025
Citation: Aarattuthodi, S., Kang, D.S., Gupta, S., Chen, P.R., Redel, B.K., Matuha, M., Mohammed, H., Sinha, A. 2025. Cryopreservation of biological materials: applications and economic perspectives. In Vitro Cellular and Developmental Biology - Animal. https://doi.org/10.1007/s11626-025-01027-0.
DOI: https://doi.org/10.1007/s11626-025-01027-0

Interpretive Summary: Not required

Technical Abstract: Cryopreservation is a transformative technology that allows for the long-term storage of biological materials by cooling them to extremely low temperatures at which metabolic and biochemical processes are effectively slowed or halted. Cryopreservation utilizes various techniques to minimize ice crystal formation and cellular damage during freezing and thawing processes. This technology has broad applications in the fields of medicine, agriculture, and conservation, spanning across stem cell research, reproductive and regenerative medicine, organ transplantation, and cell-based therapies each with significant economic implications. While current techniques and their associated costs present certain challenges, ongoing research advancements related to cryoprotectants, cooling methods, and automation promise to enhance efficiency and accessibility, potentially broadening the technology's impact across various sectors. This review focuses on the applications of cryopreservation, research advancements, and economic implications, emphasizing the importance of continued research to overcome the current limitations.