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Research Project: Intervention Strategies to Control and Eradicate Foreign Animal Diseases of Swine

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Title: African swine fever virus biotype identification tool

Author
item Dinhobl, Mark
item Spinard Iii, Edward
item BIRTLERY, HILLARY - Oak Ridge Institute For Science And Education (ORISE)
item TESLER, NICOLAS - Oak Ridge Institute For Science And Education (ORISE)
item MASEMBE, CHARLES - Makerere University
item RIBECA, PAOLO - Uk Health Security Agency
item Borca, Manuel
item Gladue, Douglas

Submitted to: Microbiology Resource Announcements
Publication Type: Rapid Release Publication
Publication Acceptance Date: 8/1/2024
Publication Date: 2/11/2025
Citation: Dinhobl, M.W., Spinard Iii, E.J., Birtlery, H., Tesler, N., Masembe, C., Ribeca, P., Borca, M.V., Gladue, D.P. 2025. African swine fever virus biotype identification tool. Microbiology Resource Announcements. 14(2). https://doi.org/10.1128/mra.00530-24.
DOI: https://doi.org/10.1128/mra.00530-24

Interpretive Summary: This reports a free to use public tool to aid in African swine fever classification by biotype.

Technical Abstract: African swine fever virus biotyping is a recently described classification technique that is based on an isolate’s encoded proteome. In short, proteomes are compared and grouped based on unsupervised machine learning. This tool analyzes an uploaded ASFV genome and will report its closest matches along with its ASFV biotype.