Location: Poultry Production and Product Safety Research
Title: Complete genome sequence of an avian pathogenic Escherichia coli strain isolated from poultryAuthor
JIA, XINGLIN - Iowa State University | |
PHILLIPS, GREGORY - Iowa State University | |
Lyte, Joshua - Josh |
Submitted to: Microbiology Resource Announcements
Publication Type: Peer Reviewed Journal Publication Acceptance Date: 8/1/2023 Publication Date: 9/21/2023 Citation: Jia, X., Phillips, G., Lyte, J.M. 2023. Complete genome sequence of an avian pathogenic Escherichia coli strain isolated from poultry. Microbiology Resource Announcements. 12(10):e0042423. https://doi.org/10.1128/MRA.00424-23. DOI: https://doi.org/10.1128/MRA.00424-23 Interpretive Summary: Escherichia coli are normally a non-disease causing bacteria that are typically found in the gut of mammals, including humans, and avians, including poultry. In chickens, some strains of E. coli can, for largely unknown reasons, suddenly cause severe disease. These strains of E. coli are specifically termed 'avian pathogenic E. coli.', abbreviated as APEC. In poultry meat, APEC can act as a foodborne pathogen as it has been associated with urinary tract infections in people. Therefore it is imperative to find what may cause an otherwise normal non-disease causing E. coli to become disease causing in chickens. In this publication, we sequenced and report the genome of a strain of APEC. This will likely help other researchers identify possible genetic markers that may serve as unique identifiers that provide insight into predicting if a normal E. coli may become disease-causing. Technical Abstract: Avian pathogenic Escherichia coli found in the avian intestinal tract can cause systemic disease in birds and act as a foodborne zoonotic pathogen associated with human disease. Here, we report the draft genome sequence of E. coli strain H1998 isolated from an air sac of a chicken with colisepticemia. |