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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Food Safety and Enteric Pathogens Research » Research » Publications at this Location » Publication #399531
Research Project: Intestinal Microbial Ecology and Non-Antibiotic Strategies to Limit Shiga Toxin-Producing Escherichia coli (STEC) and Antimicrobial Resistance Transmission in Food Animals

Location: Food Safety and Enteric Pathogens Research

Title: Phenotypic and genomic comparison of human outbreak and cattle-associated Escherichia coli O157:H7

Author
item PEROUTKA-BIGUS, NATHAN - Oak Ridge Institute For Science And Education (ORISE)
item NIELSEN, DANIEL - Oak Ridge Institute For Science And Education (ORISE)
item Trachsel, Julian
item MOU, KATHY - Oak Ridge Institute For Science And Education (ORISE)
item Sharma, Vijay
item Kudva, Indira
item Loving, Crystal

Submitted to: Conference Research Workers Disease Meeting
Publication Type: Abstract Only
Publication Acceptance Date: 11/21/2022
Publication Date: N/A
Citation: N/A

Interpretive Summary:

Technical Abstract: Objective: Shiga toxin-producing Escherichia coli O157:H7 (O157) are a common cause of human foodborne illnesses. Cattle are an asymptomatic reservoir of O157, with fecal contamination of meat and produce a major concern. Currently, the relationship between phenotype and genotype of O157 isolates that pose health risks to humans or exist primarily as environmental isolates is unclear. The objective was to compare diverse O157 isolates from human outbreaks or cattle origin to identify relationships between phenotype (cattle shedding, biofilm formation, cell attachment) and genotype in an attempt to predict phenotype from genome information alone.